| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2388754 | A | Intrinsic clearance in rat hepatocytes measured per 10'6 cells at 1 uM by LC/MS-MS analysis | Rattus norvegicus | 9 | ALA2385063 | cell-based format | Scientific Literature | |
| 2. | ALA2388755 | A | Intrinsic clearance in rat liver microsomes measured per mg of protein at 1 uM by LC/MS-MS analysis | Rattus norvegicus | 9 | ALA2385063 | microsome format | Scientific Literature | |
| 3. | ALA2388756 | A | Elimination half life in human plasma at 1 mM by HR-LC-MS analysis | Homo sapiens | 9 | ALA2385063 | cell-free format | Scientific Literature | |
| 4. | ALA2388757 | A | Intrinsic clearance in human liver microsomes measured per mg of protein at 1 uM by LC/MS-MS analysis | Homo sapiens | 9 | ALA2385063 | microsome format | Scientific Literature | |
| 5. | ALA2388758 | A | Elimination half life in Sprague-Dawley rat plasma at 1 mM by HR-LC-MS analysis | Rattus norvegicus | 9 | ALA2385063 | cell-free format | Scientific Literature | |
| 6. | ALA2388759 | A | Inhibition of CYP3A4 in human liver microsomes assessed as midazolam-1'-hydroxylation by LC-MS/MS analysis | Homo sapiens | 9 | ALA2385063 | microsome format | Scientific Literature | |
| 7. | ALA2388760 | P | Half life in simulated gastric fluid at 2 uM by LC-MS analysis | 9 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA2388761 | P | Half life in simulated intestinal fluid at 2 uM by LC-MS analysis | 9 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA2388762 | A | Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation by LC-MS/MS analysis | Homo sapiens | 9 | ALA2385063 | microsome format | Scientific Literature | |
| 10. | ALA2388763 | A | Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation by LC-MS/MS analysis | Homo sapiens | 9 | ALA2385063 | microsome format | Scientific Literature | |
| 11. | ALA2388764 | P | Solubility of the compound in aqueous buffer at pH 7 | 9 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 12. | ALA2388765 | P | Solubility of the compound in aqueous buffer at pH 4 | 9 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA2388769 | P | Solubility of the compound in water at pH 3.8 | 2 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA2388772 | P | n-octanol-KH2PO4-Na2HPO4 buffer partition coefficient, log D of the compound at pH 7.4 by shake flask method | 9 | ALA2385063 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA2388922 | F | Antagonist activity at dog CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Canis lupus familiaris | 27 | ALA2385063 | cell-based format | Scientific Literature | |
| 16. | ALA2388923 | F | Antagonist activity at guinea pig CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Cavia porcellus | 24 | ALA2385063 | cell-based format | Scientific Literature | |
| 17. | ALA2388924 | F | Antagonist activity at rat CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Rattus norvegicus | 27 | ALA2385063 | cell-based format | Scientific Literature | |
| 18. | ALA2388925 | F | Antagonist activity at mouse CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Mus musculus | 24 | ALA2385063 | cell-based format | Scientific Literature | |
| 19. | ALA2388926 | A | Protein binding in plasma (unknown origin) | Not specified | 27 | ALA2385063 | cell-free format | Scientific Literature | |
| 20. | ALA2388927 | B | Antagonist activity at ovine COX-1 | Ovis aries | 27 | ALA2385063 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!