# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2390658 | ADME | Time-dependent inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate at 0.14 to 100 uM incubated for 30 mins prior to substrate addition | Homo sapiens | 8 | ALA2384944 | microsome format | Scientific Literature | |
2. | ALA2388954 | ADME | Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate addition measured after 10 mins | Homo sapiens | 8 | ALA2384944 | microsome format | Scientific Literature | |
3. | ALA2389139 | ADME | Half life in human liver microsomes at 1 uM in presence of NADPH | Homo sapiens | 24 | ALA2384944 | microsome format | Scientific Literature | |
4. | ALA2389140 | ADME | Half life in rat liver microsomes at 1 uM in presence of NADPH | Rattus norvegicus | 22 | ALA2384944 | microsome format | Scientific Literature |