# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2390653 | P | Lipophilicity, log P of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA2390654 | A | Volume of distribution at steady state in Sprague-Dawley rat at <= 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
3. | ALA2390655 | A | Half life in Sprague-Dawley rat at <= 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
4. | ALA2390656 | A | Clearance in Sprague-Dawley rat at <= 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
5. | ALA2390657 | A | Clearance in rat liver microsomes | Rattus norvegicus | 5 | microsome format | Scientific Literature | ||
6. | ALA2390658 | A | Time-dependent inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate at 0.14 to 100 uM incubated for 30 mins prior to substrate addition | Homo sapiens | 8 | microsome format | Scientific Literature | ||
7. | ALA2388954 | A | Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate addition measured after 10 mins | Homo sapiens | 8 | microsome format | Scientific Literature | ||
8. | ALA2389139 | A | Half life in human liver microsomes at 1 uM in presence of NADPH | Homo sapiens | 24 | microsome format | Scientific Literature | ||
9. | ALA2389140 | A | Half life in rat liver microsomes at 1 uM in presence of NADPH | Rattus norvegicus | 22 | microsome format | Scientific Literature |