| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2388414 | A | Prodrug conversion assessed as snake venome phosphodiesterase-mediated thiophosphonate monoester formation at 5 mM | Crotalus adamanteus | 2 | assay format | Scientific Literature | ||
| 2. | ALA2388418 | A | Metabolic stability in human HuH7 cells assessed as half life of second step of hydrolysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA2388419 | P | Stability of the compound in DMEM assessed as half life of second step of hydrolysis in presence of 10% FCS | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA2388420 | A | Metabolic stability in human CEM cells assessed as half life of second step of hydrolysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2388588 | A | Stability of the compound in RPMI-1640 assessed as half life of second step of hydrolysis in presence of 10% FCS | 4 | assay format | Scientific Literature | |||
| 6. | ALA2388589 | P | Stability of the compound in DMEM assessed as half life of second step of hydrolysis | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA2388590 | A | Cytotoxicity against human HEL cells assessed as effect on cell morphology | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA2388592 | F | Antiviral activity against Vaccinia virus infected in human HEL cells assessed as reduction of virus-induced cytopathicity measured at day 3 by microscopic analysis | Vaccinia virus | 6 | organism-based format | Scientific Literature | ||
| 9. | ALA2388593 | F | Antiviral activity against Human simplex virus 2 G infected in human HEL cells assessed as reduction of virus-induced cytopathicity measured at day 3 by microscopic analysis | Human alphaherpesvirus 2 | 6 | organism-based format | Scientific Literature | ||
| 10. | ALA2388594 | F | Antiviral activity against thymidine kinase-deficient Human simplex virus 1 KOS infected in human HEL cells assessed as reduction of virus-induced cytopathicity measured at day 3 by microscopic analysis | Human alphaherpesvirus 1 | 6 | organism-based format | Scientific Literature | ||
| 11. | ALA2388595 | A | Cytotoxicity against mock-infected human CEM cells assessed as growth inhibition | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA2388596 | F | Antiviral activity against Human simplex virus 1 KOS infected in human HEL cells assessed as reduction of virus-induced cytopathicity measured at day 3 by microscopic analysis | Human alphaherpesvirus 1 | 6 | organism-based format | Scientific Literature | ||
| 13. | ALA2388597 | F | Antiviral activity against wild type HIV-2 ROD infected in human CEM cells assessed as inhibition of syncytia formation after 4 days by microscopic analysis | Human immunodeficiency virus 2 | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA2388598 | F | Antiviral activity against wild type HIV-1 3B infected in human CEM cells assessed as inhibition of syncytia formation after 4 days by microscopic analysis | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA2388599 | F | Antiviral activity against wild type HBV transfected in human HuH7 cells assessed as reduction of viral DNA level after 7 days by qPCR analysis | Hepatitis B virus | 4 | organism-based format | Scientific Literature | ||
| 16. | ALA2388600 | A | Cytotoxicity against human HuH7 cells assessed as reduction of cell density | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA2388601 | P | Stability of the compound in RPMI-1640 assessed as half life of second step of hydrolysis | 4 | small-molecule physicochemical format | Scientific Literature |
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