# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3388300 | ADME | Ratio of apparent permeability from basolateral to apical side in MDCK cells to apparent permeability from basolateral to apical side in human Caco2 cells | 10 | ALA3351337 | cell-based format | Scientific Literature | ||
2. | ALA3368735 | Functional | Cytotoxicity against human NB4 cells assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 51 | ALA3351991 | cell-based format | Scientific Literature | |
3. | ALA3368736 | Functional | Cytotoxicity against human NB4-R1 cells assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 51 | ALA3351991 | cell-based format | Scientific Literature | |
4. | ALA3075226 | Functional | Cytotoxicity against Mus musculus (mouse) L1210 cells assessed as growth inhibition after 72 hr by MTT assay | Mus musculus | 21 | ALA3045964 | cell-based format | Scientific Literature | |
5. | ALA3075227 | Functional | Cytotoxicity against Mus musculus (mouse) B16 cells assessed as growth inhibition after 72 hr by MTT assay | Mus musculus | 21 | ALA3045964 | cell-based format | Scientific Literature | |
6. | ALA2387875 | ADME | Cytotoxicity against mouse RAW264.7 cells | Mus musculus | 5 | ALA2384994 | cell-based format | Scientific Literature | |
7. | ALA2387876 | Functional | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL6 release incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by ELISA | Mus musculus | 5 | ALA2384994 | cell-based format | Scientific Literature | |
8. | ALA3387643 | Functional | Increase in permeability of lucifer yellow dye across human Caco2 cells | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
9. | ALA3387644 | Functional | Increase in permeability of lucifer yellow dye across MDCK cells | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
10. | ALA3387645 | ADME | Cytotoxicity against MDCK cells assessed as reduction in cell viability | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
11. | ALA3387646 | ADME | Cytotoxicity against human Caco2 cells assessed as reduction in cell viability | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
12. | ALA3387647 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
13. | ALA3387648 | ADME | Apparent permeability from basolateral to apical side in human Caco2 cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
14. | ALA3387649 | ADME | Permeability ratio, ratio of permeability from apical to basolateral side over basolateral to apical side in human Caco2 cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
15. | ALA3387650 | ADME | Efflux ratio, ratio of permeability from basolateral to apical side over apical to basolateral side in human Caco2 cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Homo sapiens | 10 | ALA3351337 | cell-based format | Scientific Literature | |
16. | ALA3387651 | ADME | Apparent permeability from apical to basolateral side in MDCK cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
17. | ALA3387652 | ADME | Apparent permeability from basolateral to apical side in MDCK cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
18. | ALA3387653 | ADME | Permeability ratio, ratio of permeability from apical to basolateral side over basolateral to apical side in MDCK cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
19. | ALA3387654 | ADME | Permeability ratio, ratio of permeability from basolateral to apical side over apical to basolateral side in MDCK cells at 50 uM over 2 hrs by isocratic reverse phase HPLC method | Canis lupus familiaris | 10 | ALA3351337 | cell-based format | Scientific Literature | |
20. | ALA3387655 | ADME | Ratio of apparent permeability from apical to basolateral side in MDCK cells to apparent permeability from apical to basolateral side in human Caco2 cells | 10 | ALA3351337 | cell-based format | Scientific Literature |