#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2389791	B	Activation of TLR4 in human PBMC cells assessed as AUC of IL8 release at 10 uM after 18 hrs by ELISA relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide	Homo sapiens	42	ALA2384907	cell-based format	Scientific Literature
2.	ALA2389978	B	Activation of mouse TLR4 transfected in HEK293 cells after 18 hrs by SEAP assay relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide	Mus musculus	42	ALA2384907	cell-based format	Scientific Literature
3.	ALA2389979	B	Activation of human TLR4 transfected in HEK293 cells after 18 hrs by SEAP assay relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide	Homo sapiens	42	ALA2384907	cell-based format	Scientific Literature
4.	ALA2389980	B	Activation of TLR4 in C57BL/6 mouse BMDC cells assessed as AUC of IP10 release at 5 uM after 18 hrs by ELISA relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide	Mus musculus	42	ALA2384907	cell-based format	Scientific Literature
5.	ALA2389981	B	Activation of TLR4 in C57BL/6 mouse BMDC cells assessed as AUC of IL6 release after 18 hrs by ELISA relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide	Mus musculus	42	ALA2384907	cell-based format	Scientific Literature
6.	ALA2389982	B	Activation of TLR4-mediated type 1 IFN release in C57BL/6 mouse BMDC cells after overnight incubation by luciferase reporter gene assay	Mus musculus	1	ALA2384907	cell-based format	Scientific Literature
7.	ALA2389983	B	Activation of TLR4-mediated type 1 IFN release in C57BL/6 mouse BMDC cells assessed as IP10 level after overnight incubation by ELISA	Mus musculus	1	ALA2384907	cell-based format	Scientific Literature
8.	ALA2389984	B	Activation of mouse TLR4/MD-2/CD14 complex in C57BL/6 mouse BMDC cells assessed as NFkappaB activation by SEAP assay in presence of LPS-RS	Mus musculus	1	ALA2384907	cell-based format	Scientific Literature
9.	ALA2389985	F	Induction of IL6 secretion in C57BL/6 mouse TLR4 deficient BMDC cells at 10 uM after 18 hrs by ELISA	Mus musculus	1	ALA2384907	cell-based format	Scientific Literature
10.	ALA2389986	B	Activation of mouse TLR4 transfected in HEK293 cells assessed as NFkappaB activation after 20 to 24 hrs by SEAP assay	Mus musculus	1	ALA2384907	cell-based format	Scientific Literature
11.	ALA2389987	B	Activation of human TLR4 transfected in HEK293 cells assessed as NFkappaB activation after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
12.	ALA2389988	B	Activation of human TLR9 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
13.	ALA2389989	B	Activation of human TLR8 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
14.	ALA2389990	B	Activation of human TLR7 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
15.	ALA2389991	B	Activation of human TLR5 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
16.	ALA2389992	B	Activation of human TLR4/MD-2/CD14 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
17.	ALA2389993	B	Activation of human TLR3 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature
18.	ALA2389994	B	Activation of human TLR2 transfected in HEK293 cells at 10 uM after 20 to 24 hrs by SEAP assay	Homo sapiens	1	ALA2384907	cell-based format	Scientific Literature