# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2388053 | Functional | Inhibition of human LAD2 mast cell activation assessed as compound 48/80-induced degranulation at 10 to 20 uM incubated for 30 mins prior to compound 48/80 challenge by beta-hexosaminidase release assay in presence of UV light | Homo sapiens | 2 | ALA2384912 | cell-based format | Scientific Literature | |
2. | ALA2388055 | Functional | Inhibition of human LAD2 mast cell activation assessed as compound 48/80-induced degranulation at 10 to 20 uM incubated for 30 mins prior to compound 48/80 challenge by beta-hexosaminidase release assay | Homo sapiens | 2 | ALA2384912 | cell-based format | Scientific Literature | |
3. | ALA2388057 | Functional | Inhibition of human LAD2 mast cell activation assessed as compound 48/80-induced degranulation at 100 uM incubated for 30 mins prior to compound 48/80 challenge by histamine release assay | Homo sapiens | 2 | ALA2384912 | cell-based format | Scientific Literature | |
4. | ALA2388060 | Functional | Inhibition of human LAD2 mast cell activation assessed as compound 48/80-induced degranulation at 10 uM incubated for 30 mins prior to compound 48/80 challenge by beta-hexosaminidase release assay | Homo sapiens | 1 | ALA2384912 | cell-based format | Scientific Literature | |
5. | ALA2388062 | Functional | Ratio of DSCG IC50 to compound IC50 for human LAD2 mast cell | Homo sapiens | 2 | ALA2384912 | cell-based format | Scientific Literature | |
6. | ALA2388063 | Functional | Inhibition of human LAD2 mast cell activation assessed as compound 48/80-induced degranulation incubated for 30 mins prior to compound 48/80 challenge by beta-hexosaminidase release assay | Homo sapiens | 4 | ALA2384912 | cell-based format | Scientific Literature |