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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2389009 T Toxicity in nu/nu mouse xenografted with human MOLM13 cells at 1 to 10 mg/kg, iv qd administered on days 1 to 5 and day 8 to 12 Mus musculus 1 organism-based format Scientific Literature 2. ALA2389010 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 10 mg/kg, iv qd administered on days 1 to 5 and day 8 to 12 measured after 48 days Homo sapiens 1 organism-based format Scientific Literature 3. ALA2389011 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 10 mg/kg, iv qd administered on days 1 to 5 and days 8 to 12 measured on day 16 Homo sapiens 1 organism-based format Scientific Literature 4. ALA2389012 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 3 mg/kg, iv qd administered on days 1 to 5 and days 8 to 12 measured on day 11 Homo sapiens 1 organism-based format Scientific Literature 5. ALA2389013 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 3 mg/kg, iv qd administered on days 1 to 5 and days 8 to 12 Homo sapiens 1 organism-based format Scientific Literature 6. ALA2389014 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 1mg/kg, iv qd administered on days 1 to 5 and days 8 to 12 measured on day 11 Homo sapiens 1 organism-based format Scientific Literature 7. ALA2389015 F Antitumor activity against human MOLM13 cells xenografted in nu/nu mouse at 1mg/kg, iv qd administered on days 1 to 5 and days 8 to 12 measured for 5 days Homo sapiens 1 organism-based format Scientific Literature 8. ALA2389016 T Toxicity in mouse assessed as loss of body weight at 25 mg/kg, iv for 5 days Mus musculus 1 organism-based format Scientific Literature 9. ALA2389017 T Toxicity in mouse assessed as mortality at 25 mg/kg, iv for 5 days Mus musculus 1 organism-based format Scientific Literature 10. ALA2389018 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg Rattus norvegicus 3 organism-based format Scientific Literature 11. ALA2389019 A Half life in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 4 organism-based format Scientific Literature 12. ALA2389020 A Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 4 organism-based format Scientific Literature 13. ALA2389641 A Plasma clearance in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 4 organism-based format Scientific Literature 14. ALA2389642 A AUC (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 4 organism-based format Scientific Literature 15. ALA2389792 B Inhibition of FLT3/ITD mutant-mediated stat5 phosphorylation in human MV4-11 cells after 1 hr by Western blot analysis Homo sapiens 1 cell-based format Scientific Literature 16. ALA2389793 F Cytotoxicity against human FLT3 negative U937 cells after 72 hrs by MTS assay Homo sapiens 4 cell-based format Scientific Literature 17. ALA2389794 B Inhibition of FLT3/ITD mutant phosphorylation in human MV4-11 cells after 1 hr by Western blot analysis Homo sapiens 1 cell-based format Scientific Literature 18. ALA2389795 F Cytotoxicity against human FLT3-negative K562 cells harboring wild type BCR/ABL after 72 hrs by MTS assay Homo sapiens 4 cell-based format Scientific Literature 19. ALA2389796 F Cytotoxicity against human RS4:11 cells harboring wild type FLT3 after 72 hrs by MTS assay Homo sapiens 4 cell-based format Scientific Literature 20. ALA2389797 F Cytotoxicity against human MV4-11 cells harboring FLT3/ITD mutant after 72 hrs by MTS assay Homo sapiens 4 cell-based format Scientific Literature