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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2389067 F Antipruritic activity in ICR mouse assessed as inhibition of compound 48/80-induced scratching-behavior at 100 mg/kg, po administered once before challenge relative to control Mus musculus 1 organism-based format Scientific Literature 2. ALA2389068 A Cmax in mouse at 30 mg/kg, po Mus musculus 2 organism-based format Scientific Literature 3. ALA2389069 A AUC in mouse at 30 mg/kg, po Mus musculus 2 organism-based format Scientific Literature 4. ALA2389071 A Half life in mouse at 2 mg/kg, iv Mus musculus 1 organism-based format Scientific Literature 5. ALA2389073 A Total plasma clearance in mouse at 2 mg/kg, iv Mus musculus 1 organism-based format Scientific Literature 6. ALA2389074 A Volume of distribution at steady state in mouse at 2 mg/kg, iv Mus musculus 1 organism-based format Scientific Literature 7. ALA2389076 B Selectivity ratio of Ki for human CB1 receptor to Ki for human CB2 receptor Homo sapiens 14 assay format Scientific Literature 8. ALA2389078 F Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production at 0.2 uM relative to control Homo sapiens 2 cell-based format Scientific Literature 9. ALA2389080 F Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production Homo sapiens 11 cell-based format Scientific Literature 10. ALA2389081 B Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes Homo sapiens 17 cell-based format Scientific Literature 11. ALA2389082 B Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes Homo sapiens 17 cell-based format Scientific Literature 12. ALA2388690 B Displacement of [3H]-CP-55,940 from mouse spleen CB2 receptor expressed in CHO cell membranes Mus musculus 2 cell-based format Scientific Literature 13. ALA2388849 T Toxicity in po dosed ICR mouse assessed as decrease in locomotor activity at 100 mg/kg, po Mus musculus 1 organism-based format Scientific Literature 14. ALA2388850 A Oral bioavailability in mouse at 30 mg/kg Mus musculus 2 organism-based format Scientific Literature