#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2388088	Physicochemical	Stability of the compound by glutathione trapping assay		1	ALA2385035	small-molecule physicochemical format	Scientific Literature
2.	ALA2388091	Physicochemical	Aqueous solubility of the compound		3	ALA2385035	small-molecule physicochemical format	Scientific Literature
3.	ALA2388092	Functional	Antidiabetic activity in Zucker diabetic fatty rat assessed as increase in total GLP-1 level at 0.05 to 10 mg/kg, po bid for 2 weeks measured on day 14 relative to vehicle-treated control	Rattus norvegicus	2	ALA2385035	organism-based format	Scientific Literature
4.	ALA2388093	Functional	Antidiabetic activity in Zucker diabetic fatty rat assessed as increase in plasma insulin level at 0.05 to 10 mg/kg, po bid for 2 weeks measured on day 14 relative to vehicle-treated control	Rattus norvegicus	2	ALA2385035	organism-based format	Scientific Literature
5.	ALA2388094	Functional	Antidiabetic activity in Zucker diabetic fatty rat assessed as reduction in non-fasted plasma glucose level at 0.05 to 10 mg/kg, po bid for 2 weeks measured on day 14 relative to vehicle-treated control	Rattus norvegicus	2	ALA2385035	organism-based format	Scientific Literature
6.	ALA2388095	Functional	Antidiabetic activity in Zucker diabetic fatty rat assessed as reduction in blood HbA1c level at 0.05 to 10 mg/kg, po bid for 2 weeks measured on day 14 relative to vehicle-treated control	Rattus norvegicus	2	ALA2385035	organism-based format	Scientific Literature
7.	ALA2388096	Functional	Antidiabetic activity in Zucker diabetic fatty rat assessed as increase in fecal bile acid excretion at 0.05 to 10 mg/kg, po bid for 2 weeks measured for 24 hrs post last dose relative to vehicle-treated control	Rattus norvegicus	3	ALA2385035	organism-based format	Scientific Literature
8.	ALA2388097	Functional	Antidiabetic activity in portal vein cannulated lean Sprague-Dawley rat assessed as effect on portal vein GIP level at 10 mg/kg, po measured after 3 to 8 hrs relative to vehicle-treated control	Rattus norvegicus	1	ALA2385035	organism-based format	Scientific Literature
9.	ALA2388098	Functional	Antidiabetic activity in portal vein cannulated lean Sprague-Dawley rat assessed as increase in portal vein PYY level at 10 mg/kg, po measured after 3 to 8 hrs	Rattus norvegicus	1	ALA2385035	organism-based format	Scientific Literature
10.	ALA2388099	Functional	Antidiabetic activity in portal vein cannulated lean Sprague-Dawley rat assessed as increase in portal vein total GLP-1 level at 10 mg/kg, po measured after 3 to 8 hrs	Rattus norvegicus	1	ALA2385035	organism-based format	Scientific Literature
11.	ALA2388100	Functional	In vivo inhibition of ASBT in portal vein cannulated lean Sprague-Dawley rat assessed as decrease in portal vein bile acid level at 10 mg/kg, po measured after 1 to 2 hrs relative to vehicle-treated control	Rattus norvegicus	1	ALA2385035	organism-based format	Scientific Literature
12.	ALA2388101	Functional	In vivo inhibition of ASBT in C57BL/6J mouse assessed as increase in fecal bile acid excretion measured for 24 hrs relative to 264W94	Mus musculus	7	ALA2385035	organism-based format	Scientific Literature
13.	ALA2388102	Functional	In vivo inhibition of ASBT in C57BL/6J mouse assessed as increase in fecal bile acid excretion measured for 24 hrs	Mus musculus	7	ALA2385035	organism-based format	Scientific Literature
14.	ALA2388103	ADME	Drug recovery in Sprague-Dawley rat feces at 10 mg/kg, po	Rattus norvegicus	7	ALA2385035	organism-based format	Scientific Literature
15.	ALA2388851	ADME	Half life in Sprague-Dawley rat intestine at 10 mg/kg, po	Rattus norvegicus	6	ALA2385035	organism-based format	Scientific Literature
16.	ALA2388852	Binding	Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysis	Rattus norvegicus	7	ALA2385035	cell-based format	Scientific Literature
17.	ALA2388853	Binding	Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysis	Mus musculus	7	ALA2385035	cell-based format	Scientific Literature
18.	ALA2388854	ADME	Cmax in Sprague-Dawley rat portal vein blood at 10 mg/kg, po	Rattus norvegicus	49	ALA2385035	organism-based format	Scientific Literature
19.	ALA2388855	ADME	Cmax in Sprague-Dawley rat systemic blood at 10 mg/kg, po	Rattus norvegicus	49	ALA2385035	organism-based format	Scientific Literature
20.	ALA2388856	ADME	Apparent permeability in MDCK cells expressing MDR1 at 3 uM after 60 mins by LC-MS/MS analysis	Canis lupus familiaris	49	ALA2385035	cell-based format	Scientific Literature