# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2395755 | F | Analgesic activity in Swiss albino mouse inflammatory pain model assessed as inhibition of acetic acid-induced writhing at 40 mg/kg, po administered 30 mins prior to acetic acid challenge relative to vehicle-treated control | Mus musculus | 13 | organism-based format | Scientific Literature | ||
2. | ALA2395756 | F | Analgesic activity in Swiss albino mouse inflammatory pain model assessed as inhibition of acetic acid-induced writhing at 20 mg/kg, po administered 30 mins prior to acetic acid challenge relative to vehicle-treated control | Mus musculus | 13 | organism-based format | Scientific Literature | ||
3. | ALA2395757 | F | Analgesic activity in Swiss albino mouse inflammatory pain model assessed as inhibition of acetic acid-induced writhing at 10 mg/kg, po administered 30 mins prior to acetic acid challenge relative to vehicle-treated control | Mus musculus | 12 | organism-based format | Scientific Literature | ||
4. | ALA2395758 | F | Analgesic activity in Swiss albino mouse inflammatory pain model assessed as inhibition of acetic acid-induced writhing at 5 mg/kg, po administered 30 mins prior to acetic acid challenge relative to vehicle-treated control | Mus musculus | 9 | organism-based format | Scientific Literature | ||
5. | ALA2395759 | F | Analgesic activity in Swiss albino mouse inflammatory pain model assessed as inhibition of acetic acid-induced writhing at 1 mg/kg, po administered 30 mins prior to acetic acid challenge relative to vehicle-treated control | Mus musculus | 13 | organism-based format | Scientific Literature | ||
6. | ALA2395762 | B | Selectivity index, ratio of IC50 for COX1 in mouse J774 cells to IC50 for COX2 in mouse J774 cells | Mus musculus | 13 | cell-based format | Scientific Literature | ||
7. | ALA2395763 | B | Inhibition of COX2 in mouse J774 cells assessed as inhibition of LPS-induced PGE2 production by radioimmunoassay | Mus musculus | 13 | cell-based format | Scientific Literature | ||
8. | ALA2395764 | B | Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of PGE2 production incubated for 15 mins prior to substrate addition measured after 30 mins by radioimmunoassay | Mus musculus | 13 | cell-based format | Scientific Literature |