| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2396206 | F | Inhibition of ocular permeability in streptozotocin-induced diabetic Sprague-Dawley rat at 10 mg/kg, po administered for 2 weeks after streptozotocin-challenge measured 24 hrs after final administration of compound | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2393846 | F | Inhibition of VAP-1 in streptozotocin-induced diabetic Sprague-Dawley rat plasma using [14C]-benzylamine as substrate at 10 mg/kg, po administered for 2 weeks after streptozotocin-challenge by scintillation spectrometric analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2393847 | B | Selectivity ratio of IC50 for human recombinant MAO-B to IC50 for human VAP-1 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA2393848 | B | Inhibition of human recombinant MAO-B using benzylamine as substrate after 1 hr by fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA2393849 | B | Selectivity ratio of IC50 for human recombinant MAO-A to IC50 for human VAP-1 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA2393850 | B | Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by scintillation spectrometric analysis | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
| 7. | ALA2393975 | B | Inhibition of human recombinant MAO-A using 5-hydroxytryptamine as substrate after 1 hr by fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA2393976 | B | Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by scintillation spectrometric analysis | Homo sapiens | 20 | cell-based format | Scientific Literature |
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