# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2395560 | F | Antagonist activity at human GPR55 expressed in CHO cells assessed as inhibition of lysophosphotidylinositol-induced beta-arrestin recruitment at 10 uM preincubated for 30 mins followed by lysophosphotidylinositol induction by beta-galactosidase reporter gene assay relative to control | Homo sapiens | 37 | ALA2390920 | cell-based format | Scientific Literature | |
2. | ALA2395562 | F | Agonist activity at human GPR55 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to lysophosphotidylinositol | Homo sapiens | 42 | ALA2390920 | cell-based format | Scientific Literature | |
3. | ALA2395565 | B | Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Homo sapiens | 15 | ALA2390920 | cell-based format | Scientific Literature | |
4. | ALA2395566 | B | Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Homo sapiens | 16 | ALA2390920 | cell-based format | Scientific Literature | |
5. | ALA2395567 | B | Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Rattus norvegicus | 25 | ALA2390920 | cell-based format | Scientific Literature | |
6. | ALA2395569 | B | Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Rattus norvegicus | 28 | ALA2390920 | cell-based format | Scientific Literature | |
7. | ALA2395571 | B | Agonist activity at mouse GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay | Mus musculus | 35 | ALA2390920 | cell-based format | Scientific Literature | |
8. | ALA2395573 | B | Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Homo sapiens | 40 | ALA2390920 | cell-based format | Scientific Literature | |
9. | ALA2395575 | B | Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Homo sapiens | 44 | ALA2390920 | cell-based format | Scientific Literature | |
10. | ALA2429572 | B | Agonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment assay | Homo sapiens | 22 | ALA2424638 | cell-based format | Scientific Literature | |
11. | ALA2429574 | B | Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis | Homo sapiens | 59 | ALA2424638 | cell-based format | Scientific Literature |