# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2395411 | B | Selectivity ratio of IC50 for human GPR55 to EC50 for human GPR35 | Homo sapiens | 2 | assay format | Scientific Literature | ||
2. | ALA2395561 | F | Antagonist activity at human GPR55 expressed in CHO cells assessed as inhibition of lysophosphotidylinositol-induced beta-arrestin recruitment preincubated for 30 mins followed by lysophosphotidylinositol induction by beta-galactosidase reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA2395562 | F | Agonist activity at human GPR55 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to lysophosphotidylinositol | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
4. | ALA2395563 | B | Selectivity ratio of EC50 for mouse GPR35 to EC50 for human GPR35 | 1 | assay format | Scientific Literature | |||
5. | ALA2395564 | B | Selectivity ratio of EC50 for rat GPR35 to EC50 for human GPR35 | 1 | assay format | Scientific Literature | |||
6. | ALA2395565 | B | Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA2395566 | B | Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
8. | ALA2395567 | B | Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
9. | ALA2395569 | B | Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Rattus norvegicus | 28 | cell-based format | Scientific Literature | ||
10. | ALA2395571 | B | Agonist activity at mouse GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay | Mus musculus | 35 | cell-based format | Scientific Literature | ||
11. | ALA2395573 | B | Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment at 10 uM after 90 mins by beta-galactosidase reporter gene assay relative to zaprinast | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
12. | ALA2395575 | B | Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
13. | ALA2395576 | P | Stability of the compound in aceronitrile/water at pH 8 at 1.2 mM after 2 to 4 days by LC-MS analysis in presence of ammonia and ammonium acetate | 1 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA2395577 | P | Stability of the compound in aceronitrile/water at pH 5.5 at 1.2 mM after 4 hrs by LC-MS analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA2395578 | P | Stability of the compound in aceronitrile/water at pH 3.5 at 1.2 mM after 90 mins by LC-MS analysis in presence of acetic acid and ammonium acetate | 1 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA2429569 | B | Agonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells at 100 uM after 90 mins by beta-arrestin recruitment assay relative to zaprinast | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
17. | ALA2429574 | B | Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
18. | ALA4042612 | B | Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assay | Homo sapiens | 10 | cell-based format | Scientific Literature |