Antiviral activity against Hepatitis C virus genotype 1b harboring NS5A Y93C/K26R double mutant infected in chimpanzee assessed as reduction in viral load at 2.5 mg/kg, iv administered every 8 hrs measured after 32 hrs
Antiviral activity against Hepatitis C virus genotype 1b harboring NS5A L28M mutant infected in chimpanzee assessed as reduction in viral load at 2.5 mg/kg, iv administered every 8 hrs measured after 32 hrs
Antiviral activity against Hepatitis C virus genotype 1b harboring NS5A Q24R/K26R double mutant infected in chimpanzee assessed as reduction in viral load at 2.5 mg/kg, iv administered every 8 hrs measured after 32 hrs
Antiviral activity against Hepatitis C virus genotype 1b harboring NS5A K26R mutant infected in chimpanzee assessed as reduction in viral load at 2.5 mg/kg, iv administered every 8 hrs measured after 32 hrs
Antiviral activity against Hepatitis C virus genotype 1b infected in chimpanzee assessed as log reduction in viral load at 2.5 mg/kg, iv administered every 8 hrs measured after 32 hrs relative to control