# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2394241 | B | Induction of Escherichia coli XL1 blue pUC18 DNA cleavage assessed as conversion of supercoiled DNA to relaxed circular DNA at 2 mM after 90 mins by agarose gel electrophoresis | Escherichia coli | 9 | assay format | Scientific Literature | ||
2. | ALA2394242 | B | Binding affinity to calf thymus DNA after 1.5 hrs by spectroscopic titration | Bos taurus | 4 | nucleic acid format | Scientific Literature | ||
3. | ALA2394243 | B | Binding affinity to calf thymus DNA at 20 to 80 uM after 1.5 hrs by UV-vis spectrophotometric analysis | Bos taurus | 9 | nucleic acid format | Scientific Literature | ||
4. | ALA2394244 | F | Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometric analysis | 11 | assay format | Scientific Literature | |||
5. | ALA2394245 | F | Induction of apoptosis in human HeLa cells at IC90 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis in presence of caspase-9 inhibitor Z-LEHD-FMK | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA2394246 | F | Induction of apoptosis in human HeLa cells at IC90 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis in presence of caspase-8 inhibitor Z-IETD-FMK | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA2394247 | F | Induction of apoptosis in human HeLa cells at IC90 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis in presence of caspase-3 inhibitor Z-DEVD-FMK | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA2394248 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA2394249 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M phase at 2 times IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 21.66%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
10. | ALA2394250 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at S phase at 2 times IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 16.22%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
11. | ALA2394251 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G1 phase at 2 times IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 51.97%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
12. | ALA2394252 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at 2 times IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 9.10%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
13. | ALA2394253 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M phase at IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 21.66%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
14. | ALA2394254 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at S phase at IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 16.22%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
15. | ALA2394255 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G1 phase at IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 51.97%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
16. | ALA2394256 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at IC50 after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 9.10%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
17. | ALA2394257 | A | Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
18. | ALA2394258 | F | Cytotoxicity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
19. | ALA2394259 | F | Cytotoxicity against human K562 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
20. | ALA2394413 | F | Cytotoxicity against human MDA-MB-361 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature |