# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2401044 | A | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Homo sapiens | 15 | ALA2396588 | cell-based format | Scientific Literature | |
2. | ALA2401045 | B | Selectivity ratio of IC50 for human AChE to IC50 for human BuChE | Homo sapiens | 3 | ALA2396588 | assay format | Scientific Literature | |
3. | ALA2401046 | A | Cytotoxicity against rat PC12 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Rattus norvegicus | 14 | ALA2396588 | cell-based format | Scientific Literature | |
4. | ALA2401047 | B | Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's method | Homo sapiens | 16 | ALA2396588 | single protein format | Scientific Literature | |
5. | ALA2401048 | B | Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's method | Homo sapiens | 16 | ALA2396588 | single protein format | Scientific Literature | |
6. | ALA4377055 | B | Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP-2 dye based assay | Mus musculus | 7 | ALA4376804 | cell-based format | Scientific Literature | |
7. | ALA4377056 | B | Inhibition of mouse TRPC5 expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP-2 dye based assay | Mus musculus | 7 | ALA4376804 | cell-based format | Scientific Literature | |
8. | ALA4377057 | B | Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assay | Mus musculus | 7 | ALA4376804 | cell-based format | Scientific Literature | |
9. | ALA4377058 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assay | Homo sapiens | 7 | ALA4376804 | cell-based format | Scientific Literature |