# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2399048 | A | Half life in rat at 5 mg/kg, po and 2 mg/kg, iv | Rattus norvegicus | 3 | ALA2396517 | organism-based format | Scientific Literature | |
2. | ALA2399049 | A | Total clearance in rat at 5 mg/kg, po and 2 mg/kg, iv | Rattus norvegicus | 3 | ALA2396517 | organism-based format | Scientific Literature | |
3. | ALA2399050 | A | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 3 | ALA2396517 | organism-based format | Scientific Literature | |
4. | ALA2399051 | A | AUC in rat at 5 mg/kg, po and 2 mg/kg, iv | Rattus norvegicus | 3 | ALA2396517 | organism-based format | Scientific Literature | |
5. | ALA2399052 | A | Cmax in rat at 5 mg/kg, po and 2 mg/kg, iv | Rattus norvegicus | 3 | ALA2396517 | organism-based format | Scientific Literature | |
6. | ALA2399053 | B | Inhibition of PI4K3alpha (unknown origin) | Homo sapiens | 10 | ALA2396517 | assay format | Scientific Literature | |
7. | ALA2399054 | B | Inhibition of PI4K3beta (unknown origin) | Homo sapiens | 10 | ALA2396517 | single protein format | Scientific Literature | |
8. | ALA2399055 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 15 | ALA2396517 | single protein format | Scientific Literature | |
9. | ALA2399057 | A | Metabolic stability in human liver microsomes relative to hepatic blood flow | Homo sapiens | 15 | ALA2396517 | microsome format | Scientific Literature | |
10. | ALA2399058 | A | Permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 15 | ALA2396517 | cell-based format | Scientific Literature | |
11. | ALA2399059 | P | Lipophilicity, log D of the compound at pH 7.4 | 15 | ALA2396517 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA2399060 | P | Solubility of the compound at pH 6.8 | 15 | ALA2396517 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA2399061 | P | Solubility of the compound at pH 2 | 15 | ALA2396517 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA2399062 | A | Cytotoxicity against human H1HeLa cells | Homo sapiens | 15 | ALA2396517 | cell-based format | Scientific Literature | |
15. | ALA2399063 | F | Antiviral activity against Human rhinovirus 5 assessed as protection against virus-induced cytopathic effect by cell-based assay | rhinovirus B5 | 10 | ALA2396517 | organism-based format | Scientific Literature | |
16. | ALA2399064 | F | Antiviral activity against Human rhinovirus 45 assessed as protection against virus-induced cytopathic effect by cell-based assay | rhinovirus A45 | 10 | ALA2396517 | organism-based format | Scientific Literature | |
17. | ALA2399065 | F | Antiviral activity against Human rhinovirus 89 assessed as protection against virus-induced cytopathic effect by cell-based assay | rhinovirus A89 | 11 | ALA2396517 | organism-based format | Scientific Literature | |
18. | ALA2399066 | F | Antiviral activity against Human rhinovirus 54 assessed as protection against virus-induced cytopathic effect by cell-based assay | Human rhinovirus A54 | 11 | ALA2396517 | cell-based format | Scientific Literature | |
19. | ALA2399067 | F | Antiviral activity against Human rhinovirus 8 assessed as protection against virus-induced cytopathic effect by cell-based assay | Human rhinovirus A8 | 11 | ALA2396517 | cell-based format | Scientific Literature | |
20. | ALA2399068 | F | Antiviral activity against Human rhinovirus 2 assessed as protection against virus-induced cytopathic effect by cell-based assay | rhinovirus A2 | 10 | ALA2396517 | organism-based format | Scientific Literature |