# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2399576 | ADME | Inhibition of CYP3A4/5 in human intestinal microsomes using midazolam as substrate after 4 mins | Homo sapiens | 15 | ALA2396584 | microsome format | Scientific Literature | |
2. | ALA2399577 | ADME | Inhibition of CYP2C9 in human liver microsomes using (S)-warfarin as substrate after 30 mins | Homo sapiens | 15 | ALA2396584 | microsome format | Scientific Literature | |
3. | ALA2399748 | Functional | Antiviral activity against HCV JFH-1 infected in human Huh7.5.1 cells assessed as viral core protein expression at 12.4 to 124.2 uM after 72 hrs by Western blot analysis | Hepacivirus hominis | 4 | ALA2396584 | organism-based format | Scientific Literature | |
4. | ALA2399750 | Functional | Cytotoxicity against human Huh7.5.1 cells after 72 hrs | Homo sapiens | 15 | ALA2396584 | cell-based format | Scientific Literature | |
5. | ALA3995395 | Unassigned | Antiradical activity assessed as gallic acid equivalents of Foline-Ciocalteu reagent reducing capacity at 1 mM preincubated for 5 mins followed by Na2CO3 addition measured after 90 mins | 8 | ALA3994598 | assay format | Scientific Literature | ||
6. | ALA3995396 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins | 8 | ALA3994598 | assay format | Scientific Literature | ||
7. | ALA3995397 | Functional | Antioxidant activity assessed as trolox equivalent of ABTS radical scavenging activity at 100 uM incubated for >= 5 mins | 8 | ALA3994598 | assay format | Scientific Literature | ||
8. | ALA3995398 | Physicochemical | Partition coefficient, logP of the compound in octan-1-ol and phosphate buffer at pH 7.4 at 25 degC after 2 hrs by UV-vis spectrometer | 8 | ALA3994598 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA3995399 | Functional | Antioxidant activity against tert-butyl hydroperoxide-induced lipoperoxidation in rat liver microsomal membranes incubated for 60 mins by TBARS assay | Rattus norvegicus | 8 | ALA3994598 | cell membrane format | Scientific Literature | |
10. | ALA3995400 | ADME | Cytotoxicity against human RPE1 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
11. | ALA3995401 | ADME | Cytotoxicity against human BJ cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
12. | ALA3995402 | ADME | Cytotoxicity against human PC3 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
13. | ALA3995403 | ADME | Cytotoxicity against human HepG2 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
14. | ALA3995404 | ADME | Cytotoxicity against human K562 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
15. | ALA3995405 | ADME | Cytotoxicity against human HL60 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
16. | ALA3995406 | ADME | Cytotoxicity against human MDA-MB-231 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
17. | ALA3995407 | ADME | Cytotoxicity against human MCF7 cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
18. | ALA3995408 | ADME | Cytotoxicity against human CAL51 at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature | |
19. | ALA3995409 | ADME | Cytotoxicity against human primary prostate mesenchymal cells at 0.0003 to 100 uM after 48 hrs by ATPlite assay | Homo sapiens | 10 | ALA3994598 | cell-based format | Scientific Literature |