# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2399924 | A | AUC in ICR mouse at 5 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2399925 | A | AUC in ICR mouse at 5 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
3. | ALA2399926 | A | Oral bioavailability in ICR mouse at 5 mg/kg by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2399927 | A | Elimination half life in ICR mouse at 5 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2399928 | A | Volume of distribution at steady state in ICR mouse at 5 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2399929 | A | Plasma protein binding in human at 10 to 50 uM by equilibrium dialysis | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
7. | ALA2399930 | A | Clearance in ICR mouse at 5 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2399931 | A | Plasma protein binding in dog at 10 to 50 uM by equilibrium dialysis | Canis lupus familiaris | 1 | cell-free format | Scientific Literature | ||
9. | ALA2399932 | A | Plasma protein binding in rat at 10 to 50 uM by equilibrium dialysis | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
10. | ALA2399933 | A | Metabolic stability in human liver S9 fraction assessed as compound remaining at 10 uM after 1 hr by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
11. | ALA2399934 | A | Metabolic stability in dog liver S9 fraction assessed as compound remaining at 10 uM after 1 hr by LC-MS/MS analysis | Canis lupus familiaris | 1 | subcellular format | Scientific Literature | ||
12. | ALA2399935 | A | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MDCK cells expressing MDR-1 | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
13. | ALA2399936 | A | Apparent permeability from basolateral to apical side in MDCK cells expressing MDR-1 at 10 uM after 90 mins by LC-MS/MS analysis | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
14. | ALA2399937 | A | Apparent permeability from apical to basolateral side in MDCK cells expressing MDR-1 at 10 uM after 90 mins by LC-MS/MS analysis | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
15. | ALA2399938 | A | Cytotoxicity against human HepG2 cells after 4 hrs by Alamar Blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA2399939 | P | Solubility of the compound in PBS by nephelometric analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA2399940 | A | Cytotoxicity against human Caco2 cells after 1 hr by Alamar Blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
18. | ALA2399942 | F | Resistance factor, ratio of GI50 for paclitaxel-resistant human 2008/17/4 cells to GI50 for human 2008 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2399943 | F | Growth inhibition of human 2008 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA2399944 | F | Growth inhibition of paclitaxel-resistant human 2008/17/4 cells | Homo sapiens | 2 | assay format | Scientific Literature |