# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2400677 | Binding | Activation of human recombinant AMPK at 20 uM after 30 mins relative to control | Homo sapiens | 2 | ALA2396611 | single protein format | Scientific Literature | |
2. | ALA2401228 | Binding | Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs | Rattus norvegicus | 6 | ALA2396611 | cell-based format | Scientific Literature | |
3. | ALA2401232 | Binding | Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake at 10 to 200 uM | Rattus norvegicus | 3 | ALA2396611 | cell-based format | Scientific Literature | |
4. | ALA2401233 | Binding | Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake at 5 uM after 5 hrs relative to control | Rattus norvegicus | 1 | ALA2396611 | cell-based format | Scientific Literature | |
5. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
7. | ALA5303713 | Functional | Inhibition of SARS-CoV-2 3CL-Pro proteolytic cleavage of a dual-labeled substrate by FRET. | Severe acute respiratory syndrome coronavirus 2 | 64 | ALA5303709 | assay format | EU-OPENSCREEN dataset | |
8. | ALA5303714 | Functional | Inhibition of SARS-CoV-2 3CL-Pro proteolytic cleavage of a dual-labeled substrate by FRET at 1mM DTT. | Severe acute respiratory syndrome coronavirus 2 | 64 | ALA5303710 | assay format | EU-OPENSCREEN dataset |