# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2401503 | Binding | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells by FLIPR assay relative to isradipine | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
2. | ALA2401504 | Binding | Antagonist activity at rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C expressed in HEK293 cells assessed as inhibition of end barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Oryctolagus cuniculus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
3. | ALA2401505 | Binding | Selectivity ratio of inhibition for rat voltage-dependent L-type calcium channel Cav1.3alpha-1D to inhibition for rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C at 1 uM | 1 | ALA2396637 | assay format | Scientific Literature | ||
4. | ALA2401506 | Binding | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells assessed as inhibition of end barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
5. | ALA2401507 | Binding | Selectivity ratio of inhibition for rat voltage-dependent L-type calcium channel Cav1.3alpha-1D to inhibition for rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C at 10 uM | 1 | ALA2396637 | assay format | Scientific Literature | ||
6. | ALA2399255 | Binding | Antagonist activity at rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C expressed in HEK293 cells assessed as inhibition of peak barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Oryctolagus cuniculus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
7. | ALA2399366 | Binding | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells assessed as inhibition of peak barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
8. | ALA2399367 | Binding | Selectivity ratio of IC50 for rat voltage-dependent L-type calcium channel Cav1.3alpha-1D to IC50 for rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C | 34 | ALA2396637 | assay format | Scientific Literature | ||
9. | ALA2399368 | Binding | Antagonist activity at rabbit voltage-dependent L-type calcium channel Cav1.2alpha-1C expressed in HEK293 cells by FLIPR assay | Oryctolagus cuniculus | 37 | ALA2396637 | cell-based format | Scientific Literature | |
10. | ALA2399369 | Binding | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells by FLIPR assay | Rattus norvegicus | 37 | ALA2396637 | cell-based format | Scientific Literature |