# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2401589 | F | Cytotoxicity against human EJ cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
2. | ALA2401590 | F | Cytotoxicity against human 5637 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA2401591 | F | Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA2400372 | F | Induction of apoptosis in human EJ cells assessed as decrease in procaspase-3 level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA2400373 | F | Induction of apoptosis in human EJ cells assessed as caspase-8 activation at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA2400374 | F | Induction of apoptosis in human EJ cells assessed as decrease in procaspase-9 level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA2400375 | F | Induction of apoptosis in human EJ cells assessed as increase in cytosolic cytochrome c level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA2400376 | F | Induction of apoptosis in human EJ cells assessed as disruption of mitochondria with frequent fusion between great number of vaculoes at 5 uM after 24 hrs by transmission electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2400377 | F | Induction of apoptosis in human EJ cells assessed as nuclear fragmentation at 5 uM after 24 hrs by transmission electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA2400378 | F | Induction of apoptosis in human EJ cells assessed as peripheral nuclear chromatin condensation at 5 uM after 24 hrs by transmission electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA2400379 | F | Induction of apoptosis in human EJ cells assessed as cristae swelling at 5 uM after 24 hrs by transmission electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA2400380 | F | Induction of apoptosis in human EJ cells assessed as mitochondrial matrix condensation at 5 uM after 24 hrs by transmission electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA2400527 | F | Induction of apoptosis in human EJ cells assessed as viable cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 99.6%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
14. | ALA2400528 | F | Induction of apoptosis in human EJ cells assessed as early apoptotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.01 to 0.04%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA2400529 | F | Induction of apoptosis in human EJ cells assessed as late apoptotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.08 to 0.22%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
16. | ALA2400530 | F | Induction of apoptosis in human EJ cells assessed as necrotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.28 to 0.30%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
17. | ALA2400531 | F | Induction of apoptosis in human EJ cells assessed as nuclear condensation at 5 uM after 24 hrs by Hoechst 33342 staining-based confocal microscopic analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
18. | ALA2400532 | F | Induction of apoptosis in human EJ cells assessed as formation of apoptotic bodies at 5 uM after 24 hrs by Hoechst 33342 staining-based confocal microscopic analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
19. | ALA2400533 | F | Induction of necrosis in human EJ cells assessed as disruption of membrane integrity measuring loss of microvilli at 15 uM after 1 hr by scanning electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA2400534 | F | Induction of necrosis in human EJ cells assessed as disruption of membrane integrity measuring pore formation at 15 uM after 1 hr by scanning electron microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |