# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2404651 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A3 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
2. | ALA2404652 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamidoadenosine from mouse adenosine A2A receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
3. | ALA2404653 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A1 receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
4. | ALA2404655 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adenosine A3 receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA2404656 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamidoadenosine from human adenosine A2A receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA2404657 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human adenosine A1 receptor expressed in CHO cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA2406807 | B | Selectivity ratio of Ki for human adenosine A2A receptor expressed in HEK293 cell membranes to Ki for human adenosine A3 receptor expressed in CHO cell membranes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA2406808 | B | Selectivity ratio of Ki for human adenosine A1 receptor to Ki for human adenosine A3 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA2406809 | B | Selectivity ratio of Ki for mouse adenosine A1 receptor to Ki for mouse adenosine A3 receptor | Mus musculus | 1 | assay format | Scientific Literature | ||
10. | ALA2406810 | B | Selectivity ratio of Ki for mouse adenosine A2A receptor to Ki for mouse adenosine A3 receptor | Mus musculus | 1 | assay format | Scientific Literature | ||
11. | ALA2406811 | F | Antiallodynic activity in adenosine A3 receptor knockout CD-1 mouse chronic constriction injury-induced neuropathic pain model assessed as reversal of mechanoallodynia at 3 micromol/kg, ip measured 1 to 5 hrs post-treatment | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA2406812 | F | Antiallodynic activity in CD-1 mouse chronic constriction injury-induced neuropathic pain model assessed as reversal of mechanoallodynia at 3 micromol/kg, ip measured 1 to 5 hrs post-treatment in presence of MRS1523 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2406813 | F | Antiallodynic activity in CD-1 mouse chronic constriction injury-induced neuropathic pain model assessed as effect on contralateral paw withdrawal threshold at 3 micromol/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA2406814 | F | Antiallodynic activity in CD-1 mouse chronic constriction injury-induced neuropathic pain model assessed as reversal of mechanoallodynia at 3 micromol/kg, ip at 1 hr post-treatment | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA2403960 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production up to 10 uM preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
16. | ALA2403961 | F | Agonist activity at mouse adenosine A3 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
17. | ALA2403962 | F | Agonist activity at mouse adenosine A3 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 4 | cell-based format | Scientific Literature | ||
18. | ALA2403963 | F | Activity at mouse adenosine A3 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to 2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide | Mus musculus | 12 | cell-based format | Scientific Literature | ||
19. | ALA2403964 | F | Activity at human adenosine A3 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated cAMP production at 10 uM preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to 5'-N-ethylcarboxamidoadenosine | Homo sapiens | 5 | cell-based format | Scientific Literature |