| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2405217 | B | Activation of ClC-3 in human CNE2Z cells assessed as increase in chloride current in outward and inward direction at +80mV holding potential at 1 uM by whole-cell patch clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2405219 | F | Cytotoxicity against mouse H22 cells expressing mutated alpha-1 Na+/K+-ATPase assessed as growth inhibition after 48 hrs by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA2405220 | F | Cytotoxicity against mouse S180 cells expressing mutated alpha-1 Na+/K+-ATPase assessed as growth inhibition after 48 hrs by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA2405396 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 50 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of ClC-3 siRNA (Rvb = 1.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2405397 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 50 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of NPPB (Rvb = 2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2405398 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 50 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of tamoxifen (Rvb = 1.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2405399 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 50 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2405400 | F | Induction of apoptosis in human CNE2Z cells assessed as activation of caspase-8 at 1 to 50 uM after 24 hrs by luminometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2405401 | F | Induction of apoptosis in human CNE2Z cells assessed as activation of caspase-3/7 at 1 to 50 uM after 24 hrs by luminometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2405404 | F | Induction of apoptosis in human CNE2Z cells assessed as increase in apoptotic cell level at 1 to 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA2405406 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 5 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of ClC-3 siRNA (Rvb = 1.3%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA2405407 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 1 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of ClC-3 siRNA (Rvb = 1.3%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2405409 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 5 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of NPPB (Rvb = 2%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA2405410 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 1 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of NPPB (Rvb = 2%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA2405412 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 5 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of tamoxifen (Rvb = 1.5%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2405413 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 1 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis in presence of tamoxifen (Rvb = 1.5%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2405582 | F | Cell cycle arrest in human CNE2Z cells assessed as accumulation at sub-G1 phase at 5 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.1%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA2405583 | F | Upregulation of ClC-3 protein expression in human CNE2Z cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA2405586 | B | Activation of ClC-3 in human CNE2Z cells assessed as increase in chloride current density at +80mV holding potential at 1 uM by whole-cell patch clamp method relative to vehicle-treated control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA2405587 | F | Cytotoxicity against adriamycin-resistant human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature |
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