# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2405793 | T | Toxicity in po dosed ferret assessed as first emetic dose by measuring occurrence of vomiting episode after 6 hrs | Mustela putorius furo | 3 | organism-based format | Scientific Literature | ||
2. | ALA2405794 | A | Binding affinity to human serum albumin | Homo sapiens | 4 | single protein format | Scientific Literature | ||
3. | ALA2405796 | F | Inhibition of LPS-induced neutrophilia in ferret COPD model BAL-fluid at 0.1 mg/kg, po | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
4. | ALA2405797 | F | Inhibition of LPS-induced neutrophilia in ferret COPD model BAL-fluid at 0.01 mg/kg, po | Mustela putorius furo | 2 | organism-based format | Scientific Literature | ||
5. | ALA2405799 | F | Inhibition of TNFalpha production in human PBMC | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2405800 | F | Inhibition of TNFalpha production in human whole blood | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
7. | ALA2405801 | F | Inhibition of LPS-induced neutrophil accumulation in rat lung at 0.1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2405802 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 1 | microsome format | Scientific Literature | ||
9. | ALA2405803 | B | Inhibition of human ERG at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA2405804 | A | Intrinsic clearance in dog liver microsomes | Canis lupus familiaris | 1 | microsome format | Scientific Literature | ||
11. | ALA2405805 | A | Cmax in rat at 3 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2405806 | A | Volume of distribution in rat at 3 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2405807 | A | Half life in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA2405808 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA2405809 | A | Clearance in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA2405810 | B | Inhibition of bovine retina PDE6 | Bos taurus | 1 | assay format | Scientific Literature | ||
17. | ALA2405811 | B | Inhibition of human recombinant PDE10A | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA2405812 | B | Inhibition of human recombinant PDE11A | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA2405813 | B | Inhibition of human recombinant PDE8A | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA2405814 | B | Inhibition of human recombinant PDE9A | Homo sapiens | 1 | single protein format | Scientific Literature |