# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2404231 | B | Binding affinity to DNA (unknown origin) at 100 uM after 2 hrs by UV-Vis absorption spectroscopic analysis | Not specified | 4 | assay format | Scientific Literature | ||
2. | ALA2404232 | F | Induction of apoptosis in human PANC1 cells assessed as PARP cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA2404233 | F | Induction of apoptosis in human T98G cells assessed as PARP cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2404234 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-9 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA2404235 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-8 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA2404236 | F | Induction of apoptosis in human T98G cells assessed as procaspase-9 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA2404237 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-7 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA2404238 | F | Induction of apoptosis in human T98G cells assessed as procaspase-8 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2404239 | F | Induction of apoptosis in human T98G cells assessed as procaspase-7 cleavage at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA2404245 | F | Downregulation of total Bid expression in human PANC1 cells at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA2404246 | F | Downregulation of Bcl-xL expression in human PANC1 cells at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA2404247 | F | Downregulation of total Bid expression in human T98G cells at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA2404249 | F | Downregulation of Bcl-xL expression in human T98G cells at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA2404863 | F | Induction of mitochondrial transmembrane depolarization in human PANC1 cells at 30 uM after 24 hrs by JC1 staining-based flow cytometric analysis (Rvb = 2.7%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA2404865 | F | Induction of mitochondrial transmembrane depolarization in human T98G cells at 30 uM after 24 hrs by JC1 staining-based flow cytometric analysis (Rvb = 10.26%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA2404866 | F | Induction of apoptosis in human PANC1 cells at 30 uM after 24 hrs by dUTP-FITC staining-based TUNEL assay (Rvb = 0.17%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA2404868 | F | Induction of apoptosis in human T98G cells at 30 uM after 24 hrs by dUTP-FITC staining-based TUNEL assay (Rvb = 1.88%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA2404869 | F | Induction of apoptosis in human PANC1 cells at 30 uM after 24 hrs by 7-AAD-based FACS flow cytometric analysis (Rvb = 5.18%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2404870 | F | Induction of apoptosis in human T98G cells at 30 uM after 24 hrs by 7-AAD-based FACS flow cytometric analysis (Rvb = 5.3%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA2404871 | F | Induction of apoptosis in human T98G cells assessed as induction of DNA damage at 20 uM after 24 hrs by comet assay relative to untreated control | Homo sapiens | 4 | cell-based format | Scientific Literature |