# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2404621 | B | Ratio of inhibition for rat brain voltage-gated sodium channel Nav1.2 F385C mutant to inhibition of rat brain voltage-gated sodium channel Nav1.2 assessed as increase in residual current | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
2. | ALA2404622 | B | Ratio of Kd for rat brain voltage-gated sodium channel Nav1.2 F385C mutant to Kd for rat brain voltage-gated sodium channel Nav1.2 | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
3. | ALA2404624 | B | Binding affinity to rat voltage-gated sodium channel Nav1.2 expressed in Xenopus laevis oocytes | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
4. | ALA2404625 | B | Inhibition of rat voltage-gated sodium channel Nav1.2-mediated current expressed in Xenopus laevis oocytes at 10 uM by two-electrode voltage-clamp electrophysiology relative to control | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
5. | ALA4381880 | B | Inhibition of Nav1.2/Nav1.4 (unknown origin) expressed in Xenopus laevis oocytes at -80 mV holding potential by two electrode voltage-clamp assay | Homo sapiens | 3 | cell-based format | Scientific Literature |