# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2406204 | B | Inhibition of CDK9-mediated RNA polymerase 2 phosphorylation at ser2 in human G361 cells at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA2406205 | B | Inhibition of CDK2/4-mediated retinoblastoma protein phosphorylation at ser780 in human G361 cells at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA2406208 | F | Induction of apoptosis in human G361 cells assessed as decrease in Mcl-1 protein level at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA2406209 | F | Induction of apoptosis in human G361 cells assessed as induction of PARP-1 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA2406210 | F | Induction of apoptosis in human G361 cells assessed as induction of caspase-9 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
6. | ALA2406211 | F | Induction of apoptosis in human G361 cells assessed as induction of caspase-3 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA2406212 | F | Induction of apoptosis in human G361 cells assessed as induction of caspase-7 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
8. | ALA2406213 | F | Induction of apoptosis in human G361 cells assessed as caspase 9 activation using Ac-DEHD-AMC as substrate at 300 nM after 24 hrs by fluorimetry assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA2406214 | F | Induction of apoptosis in human G361 cells assessed as caspase 3/7 activation using Ac-DEVD-AMC as substrate at 300 nM after 24 hrs by fluorimetry assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
10. | ALA2406215 | F | Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
11. | ALA2406216 | F | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
12. | ALA2406217 | F | Cytotoxicity against human HOS cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
13. | ALA2406218 | F | Cytotoxicity against human G361 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
14. | ALA2406219 | F | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
15. | ALA2406220 | F | Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
16. | ALA2406224 | B | Inhibition of human recombinant CDK1 | Homo sapiens | 27 | single protein format | Scientific Literature | ||
17. | ALA2406225 | B | Inhibition of human recombinant CDK2/Cyclin E expressed in baculovirus infected sf9 cells using histone H1 as substrate | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
18. | ALA2405062 | F | Induction of apoptosis in human G361 cells assessed as decrease in Mcl-1 at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
19. | ALA2405063 | B | Ratio of roscovitine IC50 to compound IC50 for human recombinant CDK2/Cyclin E | Homo sapiens | 3 | protein complex format | Scientific Literature |