# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2406208 | Functional | Induction of apoptosis in human G361 cells assessed as decrease in Mcl-1 protein level at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
2. | ALA2406209 | Functional | Induction of apoptosis in human G361 cells assessed as induction of PARP-1 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
3. | ALA2406210 | Functional | Induction of apoptosis in human G361 cells assessed as induction of caspase-9 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
4. | ALA2406211 | Functional | Induction of apoptosis in human G361 cells assessed as induction of caspase-3 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
5. | ALA2406212 | Functional | Induction of apoptosis in human G361 cells assessed as induction of caspase-7 clevage at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
6. | ALA2406213 | Functional | Induction of apoptosis in human G361 cells assessed as caspase 9 activation using Ac-DEHD-AMC as substrate at 300 nM after 24 hrs by fluorimetry assay | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
7. | ALA2406214 | Functional | Induction of apoptosis in human G361 cells assessed as caspase 3/7 activation using Ac-DEVD-AMC as substrate at 300 nM after 24 hrs by fluorimetry assay | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature | |
8. | ALA2406215 | Functional | Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
9. | ALA2406216 | Functional | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
10. | ALA2406217 | Functional | Cytotoxicity against human HOS cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
11. | ALA2406218 | Functional | Cytotoxicity against human G361 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
12. | ALA2406219 | Functional | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
13. | ALA2406220 | Functional | Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by calcein AM staining-based fluoroscence assay | Homo sapiens | 28 | ALA2401709 | cell-based format | Scientific Literature | |
14. | ALA2406224 | Binding | Inhibition of human recombinant CDK1 | Homo sapiens | 27 | ALA2401709 | single protein format | Scientific Literature | |
15. | ALA2406225 | Binding | Inhibition of human recombinant CDK2/Cyclin E expressed in baculovirus infected sf9 cells using histone H1 as substrate | Homo sapiens | 27 | ALA2401709 | cell-based format | Scientific Literature | |
16. | ALA2405062 | Functional | Induction of apoptosis in human G361 cells assessed as decrease in Mcl-1 at 300 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 7 | ALA2401709 | cell-based format | Scientific Literature |