# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2410843 | B | Non-competitive antagonist activity at human alpha4beta2 nAChR expressed in HEK-tsA201 cells assessed as intracellular calcium level at 0.1 to 100 uM by fluorescence plate reader analysis in presence of epibatidine | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2410844 | B | Agonist activity at human alpha4beta2 nAChR | Homo sapiens | 27 | protein complex format | Scientific Literature | ||
3. | ALA2410845 | B | Agonist activity at human alpha3beta4 nAChR | Homo sapiens | 27 | protein complex format | Scientific Literature | ||
4. | ALA2410846 | B | Selectivity ratio of IC50 for human alpha3beta4 nAChR to IC50 for human alpha4beta2 nAChR | Homo sapiens | 27 | assay format | Scientific Literature | ||
5. | ALA2410847 | B | Antagonist activity at human alpha3beta4 nAChR expressed in HEK-tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium level by fluorescence plate reader analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
6. | ALA2410848 | B | Antagonist activity at human alpha4beta2 nAChR expressed in HEK-tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium level by fluorescence plate reader analysis | Homo sapiens | 29 | cell-based format | Scientific Literature |