# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2412619 | B | Binding affinity to human VDR by fluorescence polarization assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
2. | ALA2412620 | B | Activation of VDR in mouse C3H10T1/2 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
3. | ALA2412621 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Gli1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to 20(S)-hydroxycholesterol and 22(S)-hydroxycholesterol | Mus musculus | 12 | cell-based format | Scientific Literature |