# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2411991 | B | Activation of VDR in human DaOY cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 48 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA2411992 | B | Inhibition of Hedgehog signaling in human DaOY cells assessed as downregulation of Gli1 mRNA expression after 48 hrs by RT-PCR analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA2411993 | B | Activation of VDR in mouse ASZ001 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 48 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
4. | ALA2411995 | B | Inhibition of Hedgehog signaling in mouse ASZ001 cells assessed as downregulation of Gli1 mRNA expression after 48 hrs by RT-PCR analysis | Mus musculus | 7 | cell-based format | Scientific Literature | ||
5. | ALA2411996 | B | Activation of VDR in human HT-29 assessed as upregulation of Cyp24A1 mRNA expression after 6 hrs by Northern blotting analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA2411998 | B | Activation of VDR in mouse M210B4 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
7. | ALA2412000 | B | Inhibition of Hedgehog signaling in mouse M210B4 cells assessed as downregulation of Ptch mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
8. | ALA2412001 | B | Inhibition of Hedgehog signaling in mouse M210B4 cells assessed as downregulation of Gli1 mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
9. | ALA2412002 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Ptch mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
10. | ALA2412003 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Gli1 mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
11. | ALA2412619 | B | Binding affinity to human VDR by fluorescence polarization assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
12. | ALA2412620 | B | Activation of VDR in mouse C3H10T1/2 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
13. | ALA2412621 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Gli1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to 20(S)-hydroxycholesterol and 22(S)-hydroxycholesterol | Mus musculus | 12 | cell-based format | Scientific Literature | ||
14. | ALA3271133 | B | Inhibition of hedgehog signaling pathway-mediated GLI1 mRNA expression in mouse C3H10T1/2 cells assessed as residual activity at 5 uM after 24 hrs by RT-PCR analysis relative to 20alpha-hydroxycholesterol/22(S)-hydroxycholesterol | Mus musculus | 28 | cell-based format | Scientific Literature | ||
15. | ALA3271135 | B | Activation of VDR in mouse C3H10T1/2 cells assessed as upregulation of CYP24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 28 | cell-based format | Scientific Literature | ||
16. | ALA3271137 | B | Inhibition of hedgehog signaling pathway-mediated GLI1 mRNA expression in mouse C3H10T1/2 cells after 24 hrs by RT-PCR analysis | Mus musculus | 8 | cell-based format | Scientific Literature | ||
17. | ALA3271508 | B | Inhibition of hedgehog signaling pathway-mediated PTCH mRNA expression in mouse C3H10T1/2 cells after 24 hrs by RT-PCR analysis | Mus musculus | 8 | cell-based format | Scientific Literature | ||
18. | ALA3271509 | B | Inhibition of hedgehog signaling pathway-mediated GLI1 mRNA expression in mouse ASZ001 cells after 24 hrs by RT-PCR analysis | Mus musculus | 8 | cell-based format | Scientific Literature | ||
19. | ALA3271510 | B | Activation of VDR in mouse ASZ001 cells assessed as upregulation of CYP24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 8 | cell-based format | Scientific Literature | ||
20. | ALA3271511 | B | Inhibition of hedgehog signaling pathway-mediated GLI1 mRNA expression in human DaOY cells after 24 hrs by RT-PCR analysis | Homo sapiens | 8 | cell-based format | Scientific Literature |