# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2412577 | Binding | Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) degradation expressed in human HeLa cells at 50 uM pretreated 12.5 mins before TNFalpha addition measured after 30 mins by ELISA | Homo sapiens | 7 | ALA2406967 | cell-based format | Scientific Literature | |
2. | ALA2412578 | Binding | Ratio of IC50 for TNFalpha-induced NF-kappaB (unknown origin) activation expressed in human HeLa cells to IC50 for TNFalpha-induced IkappaBalpha (unknown origin) phosphorylation expressed in human HeLa cells | Homo sapiens | 3 | ALA2406967 | cell-based format | Scientific Literature | |
3. | ALA2412579 | Binding | Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) phosphorylation expressed in human HeLa cells pretreated 30 mins before TNFalpha addition measured up to 120 mins by ELISA in presence of proteasome inhibitor MG-132 | Homo sapiens | 16 | ALA2406967 | cell-based format | Scientific Literature | |
4. | ALA2412580 | Binding | Inhibition of TNFalpha-induced NF-kappaB activation (unknown origin) expressed in human HeLa cells pretreated 30 mins before TNFalpha addition after 7 hrs by luciferase reporter gene assay | Homo sapiens | 21 | ALA2406967 | cell-based format | Scientific Literature |