| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3243231 | Binding | Inhibition of HDAC in human Jurkat cells assessed as increase in H3K23 acetylation at 10 uM after 12 hrs by FACS flow cytometric analysis relative to control | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 2. | ALA3243232 | Binding | Inhibition of HDAC in human Jurkat cells assessed as increase in H3K9 acetylation at 10 uM after 12 hrs by FACS flow cytometric analysis relative to control | Homo sapiens | 2 | ALA3232980 | cell-based format | Scientific Literature | |
| 3. | ALA3243235 | Functional | Increase in p21 protein expression in human Jurkat cells at 10 to 50 uM after 24 hrs by FACS flow cytometric analysis | Homo sapiens | 1 | ALA3232980 | cell-based format | Scientific Literature | |
| 4. | ALA3243236 | Functional | Increase in p21 mRNA level in human Jurkat cells at 10 to 50 uM after 24 hrs by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA3232980 | cell-based format | Scientific Literature | |
| 5. | ALA3243237 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G0/G1-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 4.16%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 6. | ALA3243238 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G1-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 65%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 7. | ALA3243239 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at S-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 19.5%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 8. | ALA3243240 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 10%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 9. | ALA3243241 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G0/G1-phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 2.39%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 10. | ALA3243242 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G1-phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 60.90%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 11. | ALA3243243 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at S-phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 20.90%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 12. | ALA3243244 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M-phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 14.30%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 13. | ALA3243245 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G0/G1-phase at 10 uM after 36 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.80%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 14. | ALA3243246 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G1-phase at 10 uM after 36 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 59.10%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 15. | ALA3243289 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at S-phase at 10 uM after 36 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 23%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 16. | ALA3243290 | Functional | Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M-phase at 10 uM after 36 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 14.20%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 17. | ALA3243291 | Functional | Induction of apoptosis in human Jurkat cells assessed as viable cells at 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based FACS flow cytometric analysis (Rvb = 99.3%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 18. | ALA3243292 | Functional | Induction of apoptosis in human Jurkat cells assessed as early apoptotic cells at 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.32%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 19. | ALA3243293 | Functional | Induction of apoptosis in human Jurkat cells assessed as late apoptotic cells at 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.0401%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature | |
| 20. | ALA3243294 | Functional | Induction of apoptosis in human Jurkat cells assessed as cell death at 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.348%) | Homo sapiens | 3 | ALA3232980 | cell-based format | Scientific Literature |
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