| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2410003 | A | Half life in mouse liver microsomes assessed as gluconoride formation at 0.4 ug/mL by HPLC-MS analysis in presence of UDPGA | Mus musculus | 13 | microsome format | Scientific Literature | ||
| 2. | ALA2410175 | A | Cytotoxicity against HDF after 72 hrs by MTS assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 3. | ALA2410176 | A | Half life in mouse liver microsomes at 0.4 ug/mL by HPLC-MS analysis in presence of NADPH | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 4. | ALA2410177 | F | Cytotoxicity against human BxPC3 cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 5. | ALA2410178 | F | Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 6. | ALA2410179 | F | Cytotoxicity against human Jurkat cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA2410180 | F | Cytotoxicity against human HUT78 cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 8. | ALA2410181 | B | Competitive inhibition of human recombinant HDAC8 by Michaelis-Menten equation analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2410187 | B | Inhibition of human recombinant HDAC5 by Michaelis-Menten equation analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 10. | ALA2410188 | B | Inhibition of human recombinant HDAC6 by Michaelis-Menten equation analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 11. | ALA2410189 | B | Inhibition of human recombinant HDAC4 by Michaelis-Menten equation analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 12. | ALA2410190 | B | Inhibition of human recombinant HDAC8 by Michaelis-Menten equation analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 13. | ALA2410191 | B | Inhibition of human recombinant HDAC2 by Michaelis-Menten equation analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 14. | ALA2410192 | B | Inhibition of human recombinant HDAC1 by Michaelis-Menten equation analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 15. | ALA3243231 | B | Inhibition of HDAC in human Jurkat cells assessed as increase in H3K23 acetylation at 10 uM after 12 hrs by FACS flow cytometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA3243232 | B | Inhibition of HDAC in human Jurkat cells assessed as increase in H3K9 acetylation at 10 uM after 12 hrs by FACS flow cytometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3243235 | F | Increase in p21 protein expression in human Jurkat cells at 10 to 50 uM after 24 hrs by FACS flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3243236 | F | Increase in p21 mRNA level in human Jurkat cells at 10 to 50 uM after 24 hrs by quantitative RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3243237 | F | Cell cycle arrest in human Jurkat cells assessed as accumulation at G0/G1-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 4.16%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA3243238 | F | Cell cycle arrest in human Jurkat cells assessed as accumulation at G1-phase at 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 65%) | Homo sapiens | 3 | cell-based format | Scientific Literature |
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