# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2410455 | B | Effect on Saccharomyces cerevisiae TDH3 up to 500 uM | Saccharomyces cerevisiae | 7 | assay format | Scientific Literature | ||
2. | ALA2410456 | B | Effect on Saccharomyces cerevisiae TDH2 up to 500 uM | Saccharomyces cerevisiae | 7 | assay format | Scientific Literature | ||
3. | ALA2410457 | B | Effect on Saccharomyces cerevisiae TDH1 up to 500 uM | Saccharomyces cerevisiae | 7 | assay format | Scientific Literature | ||
4. | ALA2410459 | T | Selectivity index, ratio of C57BL/6 mouse spleen cells to trypomastigotes forms of Trypanosoma cruzi Tulahuen infected in monkey LLC-MK2 cells | 3 | cell-based format | Scientific Literature | |||
5. | ALA2410460 | F | Trypanocidal activity against trypomastigotes forms of Trypanosoma cruzi Tulahuen infected in monkey LLC-MK2 cells after 24 hrs by beta-galactosidase reporter assay | Trypanosoma cruzi | 3 | organism-based format | Scientific Literature | ||
6. | ALA2410461 | A | Cytotoxicity against C57BL/6 mouse spleen cells after 24 hrs using propidium iodide by flow cytometry | Mus musculus | 3 | cell-based format | Scientific Literature | ||
7. | ALA2412693 | A | Cytotoxicity against Balb-c mouse 3T3 cells by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
8. | ALA2412696 | B | Non-competitive inhibition of Trypanosoma cruzi glycosomal GAPDH active site by ITC method | Trypanosoma cruzi | 3 | single protein format | Scientific Literature | ||
9. | ALA2412697 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH assessed as NAD+ Vmax by ITC method (Rvb = 0.24 +/- 0.01 uM/sec) | Trypanosoma cruzi | 7 | single protein format | Scientific Literature | ||
10. | ALA2412698 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH assessed as increase in NAD+ Km by ITC method (Rvb = 40.14 +/- 3.13 uM) | Trypanosoma cruzi | 7 | single protein format | Scientific Literature | ||
11. | ALA2412700 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH NAD+ binding site by ITC method | Trypanosoma cruzi | 7 | single protein format | Scientific Literature |