# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2410501 | B | Inhibition of MINK1 (unknown origin) at 50 times TAK1 Ki | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2410637 | B | Inhibition of MAP4K5 (unknown origin) at 50 times TAK1 Ki | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA2410638 | B | Inhibition of HGK (unknown origin) at 50 times TAK1 Ki | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA2410639 | B | Inhibition of FLT3 D835Y mutant (unknown origin) at 50 times TAK1 Ki | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA2410641 | A | Oral bioavailability in mouse at 100 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA2410642 | A | AUC (0 to infinity) in mouse at 100 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
7. | ALA2410643 | A | Cmax in mouse at 100 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA2410646 | A | Metabolic stability in human liver microsomes assessed as extraction ratio | Homo sapiens | 7 | microsome format | Scientific Literature | ||
9. | ALA2410647 | A | Metabolic stability in mouse liver microsomes assessed as extraction ratio | Mus musculus | 7 | microsome format | Scientific Literature | ||
10. | ALA2410650 | A | Oral bioavailability in mouse at 20 mg/kg | Mus musculus | 6 | organism-based format | Scientific Literature | ||
11. | ALA2410651 | A | AUC (0 to infinity) in mouse at 20 mg/kg, po | Mus musculus | 5 | organism-based format | Scientific Literature | ||
12. | ALA2410652 | A | Volume of distribution at steady state in mouse at 2 mg/kg, iv | Mus musculus | 6 | organism-based format | Scientific Literature | ||
13. | ALA2410653 | A | Cmax in mouse at 20 mg/kg, po | Mus musculus | 6 | organism-based format | Scientific Literature | ||
14. | ALA2410654 | A | AUC (0 to infinity) in mouse at 2 mg/kg, iv | Mus musculus | 6 | organism-based format | Scientific Literature | ||
15. | ALA2410655 | A | Half life in mouse at 2 mg/kg, iv | Mus musculus | 6 | organism-based format | Scientific Literature | ||
16. | ALA2410656 | A | Clearance in mouse at 2 mg/kg, iv | Mus musculus | 6 | organism-based format | Scientific Literature | ||
17. | ALA2410657 | B | Inhibition of KDR autophosphorylation overexpressed in VEGF-stimulated human HEK293 cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
18. | ALA2410822 | B | Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylation | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
19. | ALA2410823 | B | Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylation | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
20. | ALA2410824 | B | Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP | Homo sapiens | 25 | protein complex format | Scientific Literature |