| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2410609 | F | Reduction in triglyceride excursion in mouse at 10 mg/kg, po measured at 18 hrs by lipid tolerance test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 2. | ALA2410610 | B | Selectivity ratio of IC50 for human ACAT1 to IC50 for human DGAT1 | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 3. | ALA2410611 | B | Inhibition of human ACAT1 | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 4. | ALA2410612 | B | Inhibition of mouse DGAT1 | Mus musculus | 21 | single protein format | Scientific Literature | ||
| 5. | ALA2410613 | P | Lipophilicity, log D of the compound by HPLC analysis | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA2410614 | B | Inhibition of human DGAT1 | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 7. | ALA4392490 | B | Inhibition of human DGAT1 | Homo sapiens | 53 | single protein format | Scientific Literature | ||
| 8. | ALA4392491 | B | Inhibition of mouse DGAT1 | Mus musculus | 42 | single protein format | Scientific Literature | ||
| 9. | ALA4392492 | A | Inhibition of human ACAT1 | Homo sapiens | 53 | single protein format | Scientific Literature | ||
| 10. | ALA4392493 | P | Distribution coefficient, log D of compound | 20 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA4392494 | B | Inhibition of human ERG | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 12. | ALA4392496 | F | Reduction in lipid excursion in mouse at 10 mg/kg, po QD measured at 18 hrs post dose by lipid tolerance test relative to control | Mus musculus | 18 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!