# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2411661 | ADME | Therapeutic index, ratio of MCC for human HeLa cells to MIC for Helicobacter pylori | 37 | ALA2406954 | cell-based format | Scientific Literature | ||
2. | ALA2411808 | ADME | Cytotoxicity in human HeLa cells after 24 hrs by XTT assay | Homo sapiens | 39 | ALA2406954 | cell-based format | Scientific Literature | |
3. | ALA2411810 | Functional | Antibacterial activity against Helicobacter pylori after 28 hrs by microdilution method | Helicobacter pylori | 37 | ALA2406954 | organism-based format | Scientific Literature | |
4. | ALA2411811 | Binding | Binding affinity to Helicobacter pyroli flavodoxin expressed in Escherichia coli by isothermal titration calorimetry analysis | Helicobacter pylori | 41 | ALA2406954 | assay format | Scientific Literature | |
5. | ALA2434809 | Binding | Inhibition of influenza A virus HA-tagged polymerase acidic protien transfected in HEK293T cells after 24 hrs by ELISA | Influenza A virus | 27 | ALA2429796 | cell-based format | Scientific Literature | |
6. | ALA2434810 | ADME | Cytotoxicity against MDCK cells | Canis lupus familiaris | 18 | ALA2429796 | cell-based format | Scientific Literature | |
7. | ALA2434811 | Functional | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells after 48 hrs by plaque reduction assay | Influenza A virus | 27 | ALA2429796 | organism-based format | Scientific Literature | |
8. | ALA4366909 | ADME | Cytotoxicity against human HeLa cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 19 | ALA4364284 | cell-based format | Scientific Literature | |
9. | ALA4366910 | Binding | Inhibition of flavodoxin in Helicobacter pylori SS1 assessed as reduction in bacterial growth measured after 48 hrs by resazurin staining-based microdilution method | Helicobacter pylori SS1 | 19 | ALA4364284 | single protein format | Scientific Literature | |
10. | ALA4366911 | Binding | Inhibition of flavodoxin in Mnz-resistant Helicobacter pylori NCTC 11637 ATCC 43504 assessed as reduction in bacterial growth measured after 48 hrs by resazurin staining-based microdilution method | Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 | 19 | ALA4364284 | single protein format | Scientific Literature | |
11. | ALA4366912 | Binding | Inhibition of flavodoxin in Helicobacter pylori ATCC 700392 26695 assessed as reduction in bacterial growth measured after 48 hrs by resazurin staining-based microdilution method | Helicobacter pylori 26695 | 19 | ALA4364284 | single protein format | Scientific Literature | |
12. | ALA4366913 | Toxicity | Therapeutic index, ratio of MCC50 for human HeLa cells to MIC for inhibition of flavodoxin in Helicobacter pylori SS1 assessed as reduction in bacterial growth | 19 | ALA4364284 | assay format | Scientific Literature | ||
13. | ALA4366914 | Toxicity | Therapeutic index, ratio of MCC50 for human HeLa cells to MIC for inhibition of flavodoxin in Mnz-resistant Helicobacter pylori NCTC 11637 ATCC 43504 assessed as reduction in bacterial growth | 19 | ALA4364284 | assay format | Scientific Literature | ||
14. | ALA4366915 | Toxicity | Therapeutic index, ratio of MCC50 for human HeLa cells to MIC for inhibition of flavodoxin in Helicobacter pylori ATCC 700392 26695 assessed as reduction in bacterial growth | 19 | ALA4364284 | assay format | Scientific Literature | ||
15. | ALA4366933 | Toxicity | Toxicity in specific-pathogen-free C57BL/6J mouse assessed as histopathological changes in stomach by measuring hyperplasia at 40 mg/100g, po administered daily via gavage for 8 days hematoxylin-eosin staining based assay | Mus musculus | 1 | ALA4364284 | organism-based format | Scientific Literature | |
16. | ALA4366935 | Toxicity | Toxicity in specific-pathogen-free C57BL/6J mouse assessed as histopathological changes in stomach by measuring inflammation at 40 mg/100g, po administered daily via gavage for 8 days hematoxylin-eosin staining based assay | Mus musculus | 1 | ALA4364284 | organism-based format | Scientific Literature | |
17. | ALA4366936 | Toxicity | Toxicity in specific-pathogen-free C57BL/6J mouse assessed as histopathological changes in stomach by measuring necrosis of epithelium at 40 mg/100g, po administered daily via gavage for 8 days hematoxylin-eosin staining based assay | Mus musculus | 1 | ALA4364284 | organism-based format | Scientific Literature | |
18. | ALA4366941 | Physicochemical | Stability of the compound in DMSO-d6 at pH 1 incubated for 19 hrs under shaking condition by 1H-NMR analysis | 4 | ALA4364284 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA4366948 | Toxicity | Toxicity in NMRI mouse infected with Helicobacter pylori SS1 assessed as change in appetite at 0.1 to 20 mg/100g, po administered daily via gavage for 8 days starting from 1 week post-infection | Mus musculus | 2 | ALA4364284 | organism-based format | Scientific Literature | |
20. | ALA4366949 | Toxicity | Toxicity in NMRI mouse infected with Helicobacter pylori SS1 assessed as change in body weight at 0.1 to 20 mg/100g, po administered daily via gavage for 8 days starting from 1 week post-infection | Mus musculus | 2 | ALA4364284 | organism-based format | Scientific Literature |