# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2410056 | F | Reduction in plasma triglyceride level in po dosed C57BL/6J mouse administered 30 mins prior to corn oil-challenge measured after 2 hrs by oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2410057 | F | Antidiabetic activity in diet-induced obese C57BL/6J mouse model assessed as reduction in plasma glucose level at 30 mg/kg, po qd after 4 weeks by insulin tolerance test relative to high fat diet-induced control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
3. | ALA2410058 | F | Antidiabetic activity in diet-induced obese C57BL/6J mouse model assessed as reduction in plasma glucose level at 30 mg/kg, po qd after 4 weeks by oral glucose tolerance test relative to high fat diet-induced control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2410059 | F | Antiobesity activity in diet-induced obese C57BL/6J mouse model assessed as reduction in body weight gain at 30 mg/kg, po qd after 4 weeks relative to high fat diet-induced control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2410060 | F | Reduction in plasma triglyceride level in C57BL/6J mouse at 10 mg/kg, po administered 30 mins prior to corn oil-challenge measured after 2 hrs by oral lipid tolerance test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2410061 | A | Oral bioavailability in C57BL/6J mouse at 5 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2410062 | A | Clearance in C57BL/6J mouse at 1 mg/kg, iv and 5 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2410063 | A | AUC in C57BL/6J mouse at 5 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2410064 | A | Half life in C57BL/6J mouse at 1 mg/kg, iv and 5 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2410065 | A | Induction of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA2410066 | A | Induction of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA2410067 | A | Induction of CYP2E1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA2410068 | A | Induction of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA2410069 | A | Induction of CYP2B6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA2410070 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA2410071 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA2410072 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA2410073 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA2410074 | B | Binding affinity to human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA2410075 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |