# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2410261 | B | Selectivity ratio of IC50 for recombinant full length ADAM-TS4 (unknown origin) to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
2. | ALA2410262 | B | Selectivity ratio of IC50 for human recombinant ADAM-10 to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA2410263 | B | Selectivity ratio of IC50 for ADAM-9 (unknown origin) to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
4. | ALA2410264 | B | Selectivity ratio of IC50 for human recombinant MMP-7 to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
5. | ALA2410265 | B | Selectivity ratio of IC50 for human recombinant ADAM-17 to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA2410266 | B | Selectivity ratio of IC50 for MMP-16 (unknown origin) to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA2410267 | B | Selectivity ratio of IC50 for MMP-15 (unknown origin) to IC50 for human recombinant MMP-13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
8. | ALA2410268 | T | Toxicity in rat assessed as fibrodysplasia after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2410269 | T | Toxicity in rat assessed as change in connective tissue after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2410270 | T | Genotoxicity in mouse lymphoma cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA2410271 | T | Genotoxicity in Salmonella typhimurium by SOS/umu test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
12. | ALA2410272 | T | Mutagenic activity in Salmonella typhimurium by Ames assay | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
13. | ALA2410273 | B | Selectivity ratio of IC50 for human ERG channel to IC50 for human recombinant MMP13 | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA2410279 | T | Toxicity in rat assessed as change in clinical chemistry or hematological parameters after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA2410281 | T | Toxicity in rat assessed as change in body weight after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA2410282 | T | Toxicity in rat assessed as change in food and water consumption after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA2410283 | T | Toxicity in rat assessed as mortality after 28 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
18. | ALA2410285 | F | Inhibition of cartilage loss in Dunkin Hartley guinea pig spontaneous osteoarthritis model at 11 mg/kg/day, sc after 12 weeks (Rvb = 23%) | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
19. | ALA2410286 | A | Oral bioavailability in dog at 1 mg/kg | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
20. | ALA2410287 | A | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature |