| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2416376 | A | Biodistribution in Sprague-Dawley rat cerebellum assessed as increase in uptake at 0.07 to 0.11 nmol, iv pre-treated with 3 mg/kg of SB269970 measured up to 90 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2416377 | A | Biodistribution in Sprague-Dawley rat thalamus assessed as increase in uptake at 0.07 to 0.11 nmol, iv pre-treated with 3 mg/kg of SB269970 measured up to 90 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2416378 | A | Biodistribution in Sprague-Dawley rat hippocampus assessed as increase in uptake at 0.07 to 0.11 nmol, iv pre-treated with 3 mg/kg of SB269970 measured up to 90 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2415871 | A | Biodistribution in Sprague-Dawley rat frontal cortex assessed as increase in uptake at 0.07 to 0.11 nmol, iv pre-treated with 3 mg/kg of SB269970 measured up to 90 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2416070 | A | Biodistribution in Sprague-Dawley rat brain at 0.07 to 0.11 nmol, iv after 90 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2416071 | A | Drug metabolism in Sprague-Dawley rat brain assessed as intact form at 0.07 to 0.11 nmol, iv after 60 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2416072 | A | Drug metabolism in Sprague-Dawley rat brain assessed as intact form at 0.07 to 0.11 nmol, iv after 15 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2416073 | A | Drug metabolism in Sprague-Dawley rat plasma assessed as intact form at 0.07 to 0.11 nmol, iv after 60 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2416074 | A | Drug metabolism in Sprague-Dawley rat plasma assessed as intact form at 0.07 to 0.11 nmol, iv after 15 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2416075 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat brain assessed as reduction in total radioactivity at 1 nM after 30 mins by autoradiography in presence of SB269970 | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 11. | ALA2416076 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat brain assessed as reduction in total radioactivity at 1 nM after 30 mins by autoradiography in presence of unlabelled compound | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 12. | ALA2416077 | B | Binding affinity to 5-HT1A in Sprague-Dawley rat cerebral cortex at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA2416078 | B | Binding affinity to 5-HT1A in Sprague-Dawley rat hippocampus at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA2416079 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat straitum at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 15. | ALA2416147 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat pons/medulla at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 16. | ALA2416148 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat cerebellum at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 17. | ALA2416149 | A | Biodistribution in Sprague-Dawley rat brain at 0.07 to 0.11 nmol, iv after 3 to 5 mins by HPLC analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA2416150 | B | Binding affinity to 5-HT7 in Sprague-Dawley rat thalamus at 1 nM after 30 mins by autoradiography | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 19. | ALA2416151 | P | n-Octanol-sodium phosphate buffer partition coefficient, log D of the compound at pH 7.4 by shake flask method | 1 | small-molecule physicochemical format | Scientific Literature |
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