# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2415161 | B | Binding affinity to Pseudomonas aeruginosa wild-type PqsD by isothermal titration calorimetry | Pseudomonas aeruginosa | 1 | assay format | Scientific Literature | ||
2. | ALA2415162 | B | Binding affinity to Pseudomonas aeruginosa PqsD H257F mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
3. | ALA2415163 | B | Binding affinity to Pseudomonas aeruginosa PqsD C112A mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
4. | ALA2415164 | B | Binding affinity to Pseudomonas aeruginosa PqsD S317F mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
5. | ALA2415165 | B | Binding affinity to Pseudomonas aeruginosa wild-type PqsD expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
6. | ALA2415166 | B | Inhibition of Pseudomonas aeruginosa PqsD using ACoA/beta-ketodecanoic acid as substrate assessed as HHQ formation incubated for 30 mins prior to ACoA addition followed by 10 mins after treated with beta-ketodecanoic acid measured for 40 mins | Pseudomonas aeruginosa | 8 | assay format | Scientific Literature | ||
7. | ALA2415167 | B | Binding affinity to Pseudomonas aeruginosa PqsD at 20 uM incubated prior to ACoA addition by surface plasmon resonance analysis in presence of ACoA | Pseudomonas aeruginosa | 1 | assay format | Scientific Literature | ||
8. | ALA2415168 | B | Binding affinity to Pseudomonas aeruginosa PqsD at 20 uM by surface plasmon resonance analysis in presence of ACoA | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
9. | ALA2415170 | B | Inhibition of Pseudomonas aeruginosa PqsD using ACoA/beta-ketodecanoic acid as substrate assessed as HHQ formation incubated for 10 mins prior to ACoA/beta-ketodecanoic acid addition measured for 40 mins | Pseudomonas aeruginosa | 32 | assay format | Scientific Literature | ||
10. | ALA2415172 | B | Binding affinity to Pseudomonas aeruginosa PqsD at 20 uM by surface plasmon resonance analysis in absence of ACoA | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
11. | ALA3129689 | B | Inhibition of Escherichia coli RNAP assessed as incorporation of [5,6-3H]UTP at 100 uM preincubated for 10 mins followed by DNA template and ATP, CTP, GTP, UTP, [5,6-3H]UTP addition measured after 10 mins by scintillation counting analysis | Escherichia coli | 7 | assay format | Scientific Literature |