Amoebicidal activity against Acanthamoeba quina clinical isolate AcaVNAK03 assessed as minimum trophocidal concentration after 48 hrs by trypan blue exclusion assay
Amoebicidal activity against Acanthamoeba lugdunensis clinical isolate AcaVNAK02 assessed as minimum trophocidal concentration after 48 hrs by trypan blue exclusion assay
Antifungal activity against Candida albicans SC5314 infected in CD-1 mouse assessed as host survival at 25 mg/kg, po administered 4, 24, 48, 72, and 96 hrs post inoculation measured up to 12 days relative to control
Antifungal activity against Candida albicans SC5314 infected in CD-1 mouse assessed as host survival at 5 mg/kg, po administered 4, 24, 48, 72, and 96 hrs post inoculation measured up to 12 days relative to control
Antifungal activity against Candida albicans SC5314 infected in CD-1 mouse assessed as host survival at 5 mg/kg, ip administered 4, 24, 48, 72, and 96 hrs post inoculation measured up to 8 days relative to control
Antifungal activity against Candida albicans SC5314 infected in CD-1 mouse assessed as host survival at 1 mg/kg, ip administered 4, 24, 48, 72, and 96 hrs post inoculation measured up to 8 days relative to control