# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2415284 | F | Antimalarial activity against chloroquine-resistant Plasmodium yoelii N-67 infected in Swiss mouse assessed as mean survival time at 50 mg/kg, ip qd for 4 days | Plasmodium yoelii | 9 | organism-based format | Scientific Literature | ||
2. | ALA2415300 | F | Antimalarial activity against chloroquine-resistant Plasmodium yoelii N-67 infected in Swiss mouse assessed as cured animal at 50 mg/kg, ip qd for 4 days measured on day 28 post infection relative to control | Plasmodium yoelii | 9 | organism-based format | Scientific Literature | ||
3. | ALA2415302 | F | Antimalarial activity against chloroquine-resistant Plasmodium yoelii N-67 infected in Swiss mouse assessed as mouse survival at 50 mg/kg, ip qd for 4 days measured on day 28 post infection relative to control | Plasmodium yoelii | 9 | organism-based format | Scientific Literature | ||
4. | ALA2415447 | F | Antimalarial activity against chloroquine-resistant Plasmodium yoelii N-67 infected in Swiss mouse assessed as suppression of parasitaemia level at 50 mg/kg, ip qd for 4 days relative to control | Plasmodium yoelii | 9 | organism-based format | Scientific Literature | ||
5. | ALA2415448 | F | Inhibition of beta-hematin formation in Plasmodium yoelii-infected Swiss albino mouse plasma using hemin as substrate after 16 hrs | Mus musculus | 21 | cell-free format | Scientific Literature | ||
6. | ALA2415449 | F | Resistance index, ratio of IC50 for chloroquine-resistant Plasmodium falciparum K1 to IC50 for chloroquine-sensitive Plasmodium falciparum 3D7 | Plasmodium falciparum | 20 | organism-based format | Scientific Literature | ||
7. | ALA2415450 | F | Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Plasmodium falciparum | 20 | cell-based format | Scientific Literature | |||
8. | ALA2415451 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 after 72 hrs by MSF assay | Plasmodium falciparum | 21 | organism-based format | Scientific Literature | ||
9. | ALA2415452 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 after 72 hrs by MSF assay | Plasmodium falciparum | 21 | organism-based format | Scientific Literature |