# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2415454 | B | Selectivity ratio of Ki for dopamine D2 receptor in rat brain striatal membranes to Ki for 5HT2A receptor in rat brain cortical membranes | Rattus norvegicus | 2 | ALA2412990 | cell membrane format | Scientific Literature | |
2. | ALA2415455 | T | Toxicity in CF1 mouse assessed as effect on locomotor activity measuring number of crossings at 1 to 3 mg/kg, ip administered 30 mins prior ketamine challenge measured for 20 mins post challenge | Mus musculus | 1 | ALA2412990 | organism-based format | Scientific Literature | |
3. | ALA2415456 | T | Toxicity in CF1 mouse assessed as reduction in locomotor activity measuring number of crossings at 10 mg/kg, ip administered 30 mins prior ketamine challenge measured for 20 mins post challenge | Mus musculus | 1 | ALA2412990 | organism-based format | Scientific Literature | |
4. | ALA2415459 | F | Antipsychotic activity in ip dosed CF1 mouse assessed as prevention of ketamine-induced hyperlocomotion compound administered 30 mins prior ketamine challenge measured for 20 mins post challenge | Mus musculus | 1 | ALA2412990 | organism-based format | Scientific Literature | |
5. | ALA2415462 | F | Antipsychotic activity in ip dosed CF1 mouse assessed as prevention of apomorphine-induced climbing behaviour compound administered 30 mins prior apomorphine challenge measured 5 to 30 mins post challenge | Mus musculus | 1 | ALA2412990 | organism-based format | Scientific Literature | |
6. | ALA2415465 | B | Partial agonist activity at 5HT1A receptor in rat brain hippocampal membranes assessed as inhibition of [3H]-8-OH-DPAT binding to receptor after 15 mins by competition assay | Rattus norvegicus | 1 | ALA2412990 | cell membrane format | Scientific Literature | |
7. | ALA2415468 | B | Antagonist activity at alpha2 adrenoreceptor in rat brain cortical membranes assessed as inhibition of [3H]-RX821002 binding to receptor after 45 mins by competition assay in absence of GTP | Rattus norvegicus | 2 | ALA2412990 | cell membrane format | Scientific Literature | |
8. | ALA2415469 | B | Antagonist activity at alpha2 adrenoreceptor in rat brain cortical membranes assessed as inhibition of [3H]-RX821002 binding to receptor after 45 mins by competition assay in presence of GTP | Rattus norvegicus | 2 | ALA2412990 | cell membrane format | Scientific Literature | |
9. | ALA2415471 | B | Antagonist activity at 5HT2A receptor in rat brain cortical membranes assessed as inhibition of [3H]-ketanserin binding to receptor after 15 mins by competition assay in absence of GTP | Rattus norvegicus | 2 | ALA2412990 | cell membrane format | Scientific Literature | |
10. | ALA2415516 | B | Antagonist activity at 5HT2A receptor in rat brain cortical membranes assessed as inhibition of [3H]-ketanserin binding to receptor after 15 mins by competition assay in presence of GTP | Rattus norvegicus | 2 | ALA2412990 | cell membrane format | Scientific Literature | |
11. | ALA2415520 | B | Displacement of [3H]-QNB from muscarinic receptor in rat brain cortical membranes at 30 uM after 60 mins by liquid scintillation counting | Rattus norvegicus | 6 | ALA2412990 | cell membrane format | Scientific Literature | |
12. | ALA2415521 | B | Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation counting | Rattus norvegicus | 7 | ALA2412990 | cell membrane format | Scientific Literature | |
13. | ALA2415523 | B | Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation counting | Rattus norvegicus | 7 | ALA2412990 | cell membrane format | Scientific Literature | |
14. | ALA2415524 | B | Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation counting | Homo sapiens | 7 | ALA2412990 | single protein format | Scientific Literature | |
15. | ALA2415525 | B | Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation counting | Rattus norvegicus | 7 | ALA2412990 | cell membrane format | Scientific Literature | |
16. | ALA2415526 | B | Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation counting | Rattus norvegicus | 7 | ALA2412990 | cell membrane format | Scientific Literature | |
17. | ALA2415527 | B | Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation counting | Homo sapiens | 7 | ALA2412990 | single protein format | Scientific Literature | |
18. | ALA2415528 | B | Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation counting | Rattus norvegicus | 7 | ALA2412990 | cell membrane format | Scientific Literature |