| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2415809 | F | Potentiation of imatinib mesylate-induced ROS production in human imatinib mesylate-resistant LAMA-84 cells at 10 uM by spectrofluorometric analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 2. | ALA2415810 | F | Potentiation of imatinib mesylate-induced apoptosis in human imatinib mesylate-resistant LAMA-84 cells at 10 uM after 3 hrs using propidium iodide staining by FACS analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 3. | ALA2415811 | F | Induction of apoptosis in human imatinib mesylate-resistant LAMA-84 cells at 10 uM after 3 hrs using propidium iodide staining by FACS analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 4. | ALA2415813 | F | Reduction of HO-2 mRNA expression in human imatinib mesylate-resistant LAMA-84 cells at 10 uM by RT-PCR analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 5. | ALA2415814 | F | Reduction of HO-1 mRNA expression in human imatinib mesylate-resistant LAMA-84 cells at 10 uM by RT-PCR analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 6. | ALA2415815 | F | Potentiation of imatinib mesylate-induced cell cycle arrest in human imatinib mesylate-resistant LAMA-84 cells assessed as accumulation at S and G2/M phase at 10 uM after 3 hrs by FACS analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 7. | ALA2415816 | F | Cell cycle arrest in human imatinib mesylate-resistant LAMA-84 cells assessed as accumulation at S and G2/M phase at 10 uM after 3 hrs by FACS analysis | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 8. | ALA2415818 | F | Potentiation of imatinib mesylate-induced cytotoxicity in human imatinib mesylate-resistant LAMA-84 cells assessed as reduction of cell survival at 10 uM after 20 mins by ATP-lite1step assay | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 9. | ALA2415819 | F | Cytotoxicity against human imatinib mesylate-resistant LAMA-84 cells assessed as reduction of cell survival at 10 uM after 20 mins by ATP-lite1step assay | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 10. | ALA2415821 | B | Inhibition of HO-1 (unknown origin) expressed in human imatinib mesylate-resistant LAMA-84 cells assessed as bilirubin formation at 10 uM after 24 hrs relative to control | Homo sapiens | 2 | ALA2412980 | cell-based format | Scientific Literature | |
| 11. | ALA2415822 | B | Selectivity ratio of IC50 for Sprague-Dawley rat brain HO-2 to IC50 for Sprague-Dawley rat spleen microsomal HO-1 | Rattus norvegicus | 1 | ALA2412980 | tissue-based format | Scientific Literature | |
| 12. | ALA2415823 | B | Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysis | Rattus norvegicus | 22 | ALA2412980 | assay format | Scientific Literature | |
| 13. | ALA2415824 | B | Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysis | Rattus norvegicus | 22 | ALA2412980 | tissue-based format | Scientific Literature | |
| 14. | ALA3420441 | F | Cytotoxicity against human MDA-MB-231 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 15. | ALA3420442 | F | Cytotoxicity against human MCF7 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 16. | ALA3420443 | F | Cytotoxicity against human DU145 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 17. | ALA3420444 | F | Cytotoxicity against human PC3 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 18. | ALA3420445 | F | Cytotoxicity against human LNCAP cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 19. | ALA3420446 | A | Cytotoxicity against MDCK cells incubated for 72 hrs by sulforhodamine B assay | Canis lupus familiaris | 5 | ALA3414484 | cell-based format | Scientific Literature | |
| 20. | ALA3420447 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human MDA-MB-231 cells | 5 | ALA3414484 | cell-based format | Scientific Literature |
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