| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2415839 | T | Toxicity in high-fat diet fed KK/Ta Jcl mouse assessed as reduction of food intake at 3 mg/kg, po up to 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2415840 | F | Antihyperglycemic activity in high-fat diet fed KK/Ta Jcl mouse assessed as reduction of blood glucose level at 3 mg/kg, po after 6 hrs relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2415841 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2415842 | A | Volume of distribution at steady state in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2415843 | A | Total clearance in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2415844 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2415845 | A | Half life in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2415846 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2415847 | A | AUC (0 to infinity) in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2415848 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2415849 | F | Antihyperglycemic activity in Sprague-Dawley rat assessed as increase of urinary glucose excretion per 200 gram of body weight at 30 mg/kg, po up to 24 hrs | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 12. | ALA2415850 | B | Inhibition of GLUT1 in rat L6 cells assessed as reduction of [3H]-2-DG uptake at 10 uM after 15 mins by liquid scintillation counting | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2415851 | B | Inhibition of human SGLT1 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2415852 | B | Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA5129922 | B | Inhibition of human SGLT2 expressed in HEK293T cells using [14C] alpha-MDG as substrate incubated for 30 mins by scintillation counter method | Homo sapiens | 1 | cell-based format | Scientific Literature |
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