| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2416973 | F | Anticonvulsant activity in PTZ-induced ICR mouse seizure model assessed as increase in duration of tremor at 10 to 100 nmol, icv administered 30 mins prior to PTZ-challenge measured for 15 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2416974 | F | Anticonvulsant activity in icv dosed PTZ-induced ICR mouse seizure model assessed as inhibition of tonic convulsions administered 30 mins prior to PTZ-challenge measured for 15 mins | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA2416975 | F | Anticonvulsant activity in PTZ-induced ICR mouse seizure model assessed as inhibition of tonic convulsions at 1000 nmol, icv administered 30 mins prior to PTZ-challenge measured for 15 mins relative to vehicle-treated control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2417019 | F | Anticonvulsant activity in icv dosed PTZ-induced ICR mouse seizure model assessed as delay in latency of clonic convulsions administered 30 mins prior to PTZ-challenge measured for 15 mins | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA2417021 | B | Competitive binding to mouse brain GABAA receptor after 45 mins by liquid scintillation counting analysis | Mus musculus | 1 | assay format | Scientific Literature | ||
| 6. | ALA2417022 | B | Displacement of [3H]muscimol from mouse brain GABAA receptor at 100 uM after 45 mins by liquid scintillation counting analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 7. | ALA2417025 | B | Displacement of [3H]GABA from rat brain GABAB receptor at 10 uM after 30 mins by liquid scintillation counting analysis in presence of iso-guvacine | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 8. | ALA2417026 | B | Displacement of [3H]GABA from rat brain GABAB receptor at 1 uM after 30 mins by liquid scintillation counting analysis in presence of iso-guvacine | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 9. | ALA2417027 | B | Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA2417028 | B | Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA2417029 | B | Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA2417030 | B | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA2417031 | B | Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake at 100 uM after 20 mins by liquid scintillation counting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA2417032 | B | Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake at 100 uM after 20 mins by liquid scintillation counting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA2417033 | B | Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake at 100 uM after 20 mins by liquid scintillation counting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 16. | ALA2417034 | B | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake at 100 uM after 20 mins by liquid scintillation counting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature |
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