| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2417343 | B | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated at 500 uM for 20 mins before substrate addition by fluorescence assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 2. | ALA2417344 | B | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated at 10 uM for 20 mins before substrate addition by fluorescence assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 3. | ALA2417345 | B | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins before substrate addition by fluorescence assay relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 4. | ALA2416379 | B | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins before substrate addition by fluorescence assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 5. | ALA3364117 | F | Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA3364118 | F | Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA3364119 | B | Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA3364120 | B | Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA3364121 | B | Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid scintillation counting | Mus musculus | 8 | assay format | Scientific Literature | ||
| 10. | ALA3364122 | B | Displacement of [3H]CP55,940 from human CB1 expressed in CHO-K1 cells after 2 hrs by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA3364123 | B | Displacement of [3H]CP55,940 from human CB2 expressed in CHO-K1 cells after 2 hrs by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA3364437 | B | Selectivity ratio of Ki for human CB2 expressed in CHO-K1 cells to Ki for human CB1 expressed in CHO-K1 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4424992 | B | Inhibition of recombinant human FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 14. | ALA4679258 | F | Antinociceptive activity against LPS-induced inflammatory pain Sprague-Dawley rat model assessed as increase in paw withdrawal threshold at 100 mg/kg, po measured up to 6 hrs by von Frey assay | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA4679259 | A | Half life in Sprague-Dawley rat at 100 mg/kg, po measured up to 96 hrs by LC/MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4679260 | A | AUC in Sprague-Dawley rat at 100 mg/kg, po measured up to 96 hrs by LC/MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA4679261 | A | Tmax in Sprague-Dawley rat at 100 mg/kg, po measured up to 96 hrs by LC/MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA4679262 | A | Cmax in Sprague-Dawley rat at 100 mg/kg, po measured up to 96 hrs by LC/MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA4679263 | B | Inhibition of recombinant mouse sEH expressed in baculovirus expression system using MNPC as substrate by fluorescence-based assay | Mus musculus | 19 | assay format | Scientific Literature | ||
| 20. | ALA4679264 | B | Inhibition of recombinant rat sEH expressed in baculovirus expression system using MNPC as substrate by fluorescence-based assay | Rattus norvegicus | 19 | assay format | Scientific Literature |
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